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Vinorelbine CAS号 71486-22-1

基本信息

CAS(化学文摘登记)号

71486-22-1

英文名称

Vinorelbine

英文化学名

Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C4=C5C(C=CC=C6)=C6N4)(CC(C=C(CC)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C45H54N4O8

分子量

778.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine is chemically Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Vinorelbine is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-cas-71486-22-1/

相关产品

105661-07-2 (Tartrate salt) ; 125317-39-7 (Ditartrate salt)

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Vinorelbine 杂质 C CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Vinorelbine 杂质 C

英文化学名

(3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-Acetoxy-3a-ethyl-9-((2R,6R,8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

简化分子线性输入规范(SMILES)

O=C([C@]1(O)[C@]2([H])N(C)C3=C(C=C([C@]4(C(OC)=O)C[C@]5([H])C=C(CC)C[N@@](C5)CC6=C4NC7=C6C=CC=C7)C(OC)=C3)[C@]2(CCN8CC=C9)[C@]8([H])[C@]9(CC)[C@H]1OC(C)=O)OC

分子式

C45H54N4O8

分子量

778.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine Impurity C is chemically (3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-Acetoxy-3a-ethyl-9-((2R,6R,8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. It is also known as 8’-epi Vinorelbine Bitartrate. Vinorelbine Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-impurity-c-cas-N/A/

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Vinorelbine EP 杂质 D CAS号 74075-34-6

基本信息

CAS(化学文摘登记)号

74075-34-6

英文名称

Vinorelbine EP 杂质 D

英文化学名

(6′RS)-4′-Deoxy-3′,4′-didehydro-8′-norvincaleukoblastine 6′-oxide

简化分子线性输入规范(SMILES)

CN([C@]1([H])[C@@]23[C@](N4CC3)([H])[C@](C=CC4)(CC)[C@](OC(C)=O)([H])[C@]1(O)C(OC)=O)C5=C2C=C([C@@](C(OC)=O)(C[C@]6([H])C=C(CC)C[N](C6)(C7)=O)C8=C7C(C=CC=C9)=C9N8)C(OC)=C5

分子式

C45H54N4O9

分子量

794.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine EP Impurity D is chemically (6′RS)-4′-Deoxy-3′,4′-didehydro-8′-norvincaleukoblastine 6′-oxide. It is also known as Vinorelbine N’b-Oxide. Vinorelbine EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-ep-impurity-dvinorelbine-nb-oxide-cas-74075-34-6/

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(20’RS)-15’,20’-Dihydro Vinorelbine Ditartrate CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

(20’RS)-15’,20’-Dihydro Vinorelbine Ditartrate

英文化学名

(2beta,3beta,4beta,5alpha,12R,19alpha)-4-(Acetyloxy)-6,7-didehydro-15-[(2S,4RS,6S,8S)-4-ethyl-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic Acid Methyl Ester Ditartarate

简化分子线性输入规范(SMILES)

[H][C@@]1([C@](C(OC)=O)(O)[C@H](OC(C)=O)[C@@]2(C=CCN3CC[C@]41[C@@]32[H])CC)N(C)C5=C4C=C([C@@]6(C(OC)=O)C[C@]7([H])CC(CC)C[N@@](C7)CC8=C6NC9=C8C=CC=C9)C(OC)=C5.OC(C(C(O)=O)O)C(O)=O.OC(C(C(O)=O)O)C(O)=O

分子式

C45H56N4O8 : 2(C4H6O6)

分子量

781 : 2(150.1)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

(20’RS)-15’,20’-Dihydro Vinorelbine Ditartrate is chemically (2beta,3beta,4beta,5alpha,12R,19alpha)-4-(Acetyloxy)-6,7-didehydro-15-[(2S,4RS,6S,8S)-4-ethyl-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic Acid Methyl Ester Ditartarate. (20’RS)-15’,20’-Dihydro Vinorelbine Ditartrate is supplied with detailed characterization data compliant with regulatory guideline. (20’RS)-15’,20’-Dihydro Vinorelbine Ditartrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/20rs-1520-dihydro-vinorelbine-ditartrate-cas-N/A/

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Vinorelbine EP 杂质 E CAS号 23360-92-1

基本信息

CAS(化学文摘登记)号

23360-92-1

英文名称

Vinorelbine EP 杂质 E

英文化学名

Methyl (1aS,3R,11S,13S,13aR)-11-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-1a-ethyl-1a,4,5,10,11,12,13,13a-octahydro-2H-3,13-methanooxireno[2′,3′:9,10][1]azacycloundecino[5,4-b]indole-11-carboxylate

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C4=CC([C@](C5=C(CC[N@@]6C7)C8=CC=CC=C8N5)(C[C@]7([H])[C@@H]9[C@](CC)(C6)O9)C(OC)=O)=C(OC)C=C4N%10C)[C@]%10([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C46H56N4O9

分子量

809

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine EP Impurity E is chemically Methyl (1aS,3R,11S,13S,13aR)-11-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-1a-ethyl-1a,4,5,10,11,12,13,13a-octahydro-2H-3,13-methanooxireno[2′,3′:9,10][1]azacycloundecino[5,4-b]indole-11-carboxylate. It is also known as Leurosine. Vinorelbine EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-ep-impurity-e-cas-23360-92-1/

相关产品

54081-68-4 (硫酸盐)

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Vinorelbine N-Oxide CAS号 1797884-51-5

基本信息

CAS(化学文摘登记)号

1797884-51-5

英文名称

Vinorelbine N-Oxide

英文化学名

(2S,6R,8S)-8-((3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2H-2,6-methanoazecino[4,3-b]indole 2-oxide

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C[C@]4([H])C=C(CC)C[N@@+]5([O-])C4)(C6=C(C5)C(C=CC=C7)=C7N6)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C45H54N4O9

分子量

794.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine N-Oxide is chemically (2S,6R,8S)-8-((3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2H-2,6-methanoazecino[4,3-b]indole 2-oxide. Vinorelbine N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-n-oxide-cas-1797884-51-5/

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18-O-Demethyl Vinorelbine CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

18-O-Demethyl Vinorelbine

英文化学名

(2S,6R,8S)-8-((3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-4-ethyl-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indole-8-carboxylic acid

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C[C@]4([H])C=C(CC)C[N@@]5C4)(C6=C(C5)C(C=CC=C7)=C7N6)C(O)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C44H52N4O8

分子量

764.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

18-O-Demethyl Vinorelbine is chemically (2S,6R,8S)-8-((3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-4-ethyl-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indole-8-carboxylic acid. 18-O-Demethyl Vinorelbine is supplied with detailed characterization data compliant with regulatory guideline. 18-O-Demethyl Vinorelbine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/18-o-demethyl-vinorelbine-cas-N/A/

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Vinorelbine EP 杂质 K CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Vinorelbine EP 杂质 K

英文化学名

Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((2R,4R,6S,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,4,5,6,7,8,9-octahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C4=CC([C@@](C[C@]5([H])C[C@@H](CC)C[N@@]6C5)(C7=C(C6)C(C=CC=C8)=C8N7)C(OC)=O)=C(OC)C=C4N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C45H56N4O8

分子量

780.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine EP Impurity K is chemically Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((2R,4R,6S,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,4,5,6,7,8,9-octahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Vinorelbine EP Impurity K is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine EP Impurity K can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-ep-impurity-k-cas-N/A/

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Vinorelbine Ditartrate CAS号 125317-39-7

基本信息

CAS(化学文摘登记)号

125317-39-7

英文名称

Vinorelbine Ditartrate

英文化学名

Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate bis((2R,3R)-2,3-dihydroxysuccinate)

简化分子线性输入规范(SMILES)

O[C@@H](C(O)=O)[C@@H](O)C(O)=O.O[C@@H](C(O)=O)[C@@H](O)C(O)=O.CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C4=C5C(C=CC=C6)=C6N4)(CC(C=C(CC)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C45H54N4O8 : 2(C4H6O6)

分子量

778.9 : 2(150.1)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine Ditartrate is chemically Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((8R)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate bis((2R,3R)-2,3-dihydroxysuccinate). Vinorelbine Ditartrate is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine Ditartrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-ditartrate-cas-125317-39-7/

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Vinorelbine EP 杂质 G CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Vinorelbine EP 杂质 G

英文化学名

4′-Deoxy-3′alpha,4′alpha-epoxy-8′-norvincaleukoblastine

简化分子线性输入规范(SMILES)

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C4=CC([C@@](C[C@]5([H])[C@@H](O6)[C@]6(CC)C[N@@]7C5)(C8=C(C7)C(C=CC=C9)=C9N8)C(OC)=O)=C(OC)C=C4N%10C)[C@]%10([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

分子式

C45H54N4O9

分子量

795.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Vinorelbine EP Impurity G is chemically 4′-Deoxy-3′alpha,4′alpha-epoxy-8′-norvincaleukoblastine. It is also known as 5’-Norleurosine Sulfate. Vinorelbine EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Vinorelbine EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vinorelbine . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/vinorelbine-ep-impurity-g5-norleurosine-sulfate-cas-N/A/

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