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Venetoclax-N-Oxide 杂质 CAS号 2469279-00-1

基本信息

CAS(化学文摘登记)号

2469279-00-1

英文名称

Venetoclax-N-Oxide 杂质

英文化学名

4-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-1-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine 1-oxide

简化分子线性输入规范(SMILES)

ClC1=CC=C(C2=C(C[N+]3([O-])CCN(C4=CC(OC5=CN=C(NC=C6)C6=C5)=C(C(NS(C7=CC([N+]([O-])=O)=C(NCC8CCOCC8)C=C7)(=O)=O)=O)C=C4)CC3)CCC(C)(C)C2)C=C1

分子式

C45H50ClN7O8S

分子量

884.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax-N-Oxide Impurity is chemically 4-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-1-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine 1-oxide. Venetoclax-N-Oxide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax-N-Oxide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

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https://www.chemwhat.com/venetoclax-n-oxide-impurity-cas-2469279-00-1/

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Venetoclax-d8 CAS号 1257051-06-1

基本信息

CAS(化学文摘登记)号

1257051-06-1

英文名称

Venetoclax-d8

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

CC1(C)CC(C2=CC=C(Cl)C=C2)=C(CC1)CN3C([2H])([2H])C([2H])([2H])N(C4=CC(OC5=CN=C6C(C=CN6)=C5)=C(C(N[S](=O)(C7=CC([N](=O)=O)=C(NCC8CCOCC8)C=C7)=O)=O)C=C4)C([2H])([2H])C3([2H])[2H]

分子式

C45H42D8ClN7O7S

分子量

876.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax-d8 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Venetoclax-d8 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax-d8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-d8-cas-1257051-06-1/

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Venetoclax 杂质 8 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax 杂质 8

英文化学名

N-(1-(4-(N-(2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-nitrophenyl)pyridin-4(1H)-ylidene)-N-methylmethanaminium

简化分子线性输入规范(SMILES)

C/[N+](C)=C1C=CN(C2=CC=C(S(=O)(NC(C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7)=O)=O)C=C2[N+]([O-])=O)C=C1

分子式

C46H48ClN8O6S

分子量

876.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 8 is chemically N-(1-(4-(N-(2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-nitrophenyl)pyridin-4(1H)-ylidene)-N-methylmethanaminium. Venetoclax Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-8-cas-N/A/

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Venetoclax 杂质 10 CAS号 2573767-90-3

基本信息

CAS(化学文摘登记)号

2573767-90-3

英文名称

Venetoclax 杂质 10

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluoro-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

O=C(NS(=O)(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(F)C=C3OC4=CN=C(NC=C5)C5=C4

分子式

C26H24FN5O7S

分子量

569.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 10 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluoro-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Venetoclax Impurity 10 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-10-cas-2573767-90-3/

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Deschloro Venetoclax 杂质 CAS号 2573767-91-4

基本信息

CAS(化学文摘登记)号

2573767-91-4

英文名称

Deschloro Venetoclax 杂质

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

CC1(C)CCC(CN(CC2)CCN2C3=CC=C(C(NS(C4=CC=C(NCC5CCOCC5)C([N+]([O-])=O)=C4)(=O)=O)=O)C(OC6=CN=C7C(C=CN7)=C6)=C3)=C(C8=CC=CC=C8)C1

分子式

C45H51N7O7S

分子量

834.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Deschloro Venetoclax Impurity is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Deschloro Venetoclax Impurity is supplied with detailed characterization data compliant with regulatory guideline. Deschloro Venetoclax Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/deschloro-venetoclax-impurity-cas-2573767-91-4/

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Venetoclax CAS号 1257044-40-8

基本信息

CAS(化学文摘登记)号

1257044-40-8

英文名称

Venetoclax

英文化学名

4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide

简化分子线性输入规范(SMILES)

CC1(C)CC(C2=CC=C(Cl)C=C2)=C(CC1)CN3CCN(C4=CC(OC5=CN=C6C(C=CN6)=C5)=C(C(N[S](=O)(C7=CC([N](=O)=O)=C(NCC8CCOCC8)C=C7)=O)=O)C=C4)CC3

分子式

C45H50ClN7O7S

分子量

868.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax is chemically 4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide. Venetoclax is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-cas-1257044-40-8/

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Metabolite M27 CAS号 2097938-69-5

基本信息

CAS(化学文摘登记)号

2097938-69-5

英文名称

Metabolite M27

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(7-(4-chlorophenyl)-9,9-dimethyl-1,3,4,8,9,10,10a,11a-octahydro-2H,6H-benzo[e]pyrazino[2,1-b][1,3]oxazin-2-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

O=S(C(C=C1[N+]([O-])=O)=CC=C1NCC2CCOCC2)(NC(C3=C(OC4=CN=C(NC=C5)C5=C4)C=C(N6CCN(CC7=C(C8=CC=C(Cl)C=C8)CC(C)(C)CC7O9)C9C6)C=C3)=O)=O

分子式

C45H48ClN7O8S

分子量

882.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Metabolite M27 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(7-(4-chlorophenyl)-9,9-dimethyl-1,3,4,8,9,10,10a,11a-octahydro-2H,6H-benzo[e]pyrazino[2,1-b][1,3]oxazin-2-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. It is also known as 3,3′-Oxy-Venetoclax. Metabolite M27 is supplied with detailed characterization data compliant with regulatory guideline. Metabolite M27 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/metabolite-m27-cas-2097938-69-5/

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Venetoclax 杂质 7 CAS号 1228837-05-5

基本信息

CAS(化学文摘登记)号

1228837-05-5

英文名称

Venetoclax 杂质 7

英文化学名

4′-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-carbaldehyde

简化分子线性输入规范(SMILES)

O=CC1=C(C2=CC=C(Cl)C=C2)CC(C)(C)CC1

分子式

C15H17ClO

分子量

248.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 7 is chemically 4′-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-carbaldehyde. Venetoclax Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-7-cas-1228837-05-5/

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Venetoclax 杂质 I CAS号 2514648-06-5

基本信息

CAS(化学文摘登记)号

2514648-06-5

英文名称

Venetoclax 杂质 I

英文化学名

Methyl 2,4-bis(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate

简化分子线性输入规范(SMILES)

O=C(OC)C1=CC=C(OC2=CN=C(NC=C3)C3=C2)C=C1OC4=CN=C(NC=C5)C5=C4

分子式

C22H16N4O4

分子量

400.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity I is chemically Methyl 2,4-bis(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate . Venetoclax Impurity I is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity I can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-i-cas-2514648-06-5/

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Venetoclax 杂质 5 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax 杂质 5

英文化学名

1-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine 1-oxide

简化分子线性输入规范(SMILES)

CC1(C)CC(C2=CC=C(Cl)C=C2)=C(CC1)CN3CC[N+](C4=CC(OC5=CN=C6C(C=CN6)=C5)=C(C(N[S](=O)(C7=CC([N](=O)=O)=C(NCC8CCOCC8)C=C7)=O)=O)C=C4)([O-])CC3

分子式

C45H50ClN7O8S

分子量

884.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 5 is chemically 1-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine 1-oxide. Venetoclax Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-5-cas-N/A/

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