文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax 杂质 43

英文化学名

Bis(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)methane

简化分子线性输入规范(SMILES)

CC1(C)CCC(CN2CCN(CN3CCN(CC4=C(C5=CC=C(Cl)C=C5)CC(C)(C)CC4)CC3)CC2)=C(C6=CC=C(Cl)C=C6)C1

分子式

C39H54Cl2N4

分子量

649.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 43 is chemically Bis(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)methane. Venetoclax Impurity 43 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 43 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax Nitroso 杂质 4

英文化学名

1-((4′-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)-4-nitrosopiperazine

简化分子线性输入规范(SMILES)

O=NN1CCN(CC2=C(C3=CC=C(Cl)C=C3)CC(C)(C)CC2)CC1

分子式

C19H26ClN3O

分子量

347.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Nitroso Impurity 4 is chemically 1-((4′-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)-4-nitrosopiperazine. Venetoclax Nitroso Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Nitroso Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

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基本信息

CAS(化学文摘登记)号

2180923-65-1

英文名称

Venetoclax 杂质 39

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromo-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

O=C(C1=CC=C(C=C1OC2=CC3=C(NC=C3)N=C2)Br)NS(=O)(C4=CC=C(C(N(=O)=O)=C4)NCC5CCOCC5)=O

分子式

C26H24BrN5O7S

分子量

630.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 39 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromo-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Venetoclax Impurity 39 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 39 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-39-cas-2180923-65-1/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax 杂质 35

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-3′,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-fluoro-3-nitrophenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

O=C(NS(=O)(C1=CC=C(F)C([N+]([O-])=O)=C1)=O)C2=CC=C(N3CCN(CC4=C(C5=CC(C)=C(Cl)C=C5)CC(C)CC4)CC3)C=C2OC6=CN=C(NC=C7)C7=C6

分子式

C39H38ClFN6O6S

分子量

773.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 35 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-3′,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-fluoro-3-nitrophenyl)sulfonyl)benzamide. Venetoclax Impurity 35 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 35 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-35-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax N-Hydroxylamine 杂质

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methoxy)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

简化分子线性输入规范(SMILES)

O=S(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)(NC(C3=C(OC4=CN=C(NC=C5)C5=C4)C=C(N6CCN(OCC7=C(C8=CC=C(Cl)C=C8)CC(C)(C)CC7)CC6)C=C3)=O)=O

分子式

C45H50ClN7O8S

分子量

884.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax N-Hydroxylamine Impurity is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methoxy)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Venetoclax N-Hydroxylamine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax N-Hydroxylamine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-n-hydroxylamine-impurity-cas-N/A/

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基本信息

CAS(化学文摘登记)号

1228780-71-9

英文名称

Venetoclax 杂质 40

英文化学名

Tert-butyl 4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine-1-carboxylate

简化分子线性输入规范(SMILES)

CC1(CC(C(C=C2)=CC=C2Cl)=C(CC1)CN(CC3)CCN3C(OC(C)(C)C)=O)C

分子式

C24H35ClN2O2

分子量

419.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 40 is chemically Tert-butyl 4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine-1-carboxylate. Venetoclax Impurity 40 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 40 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-40-cas-1228780-71-9/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax Nitroso 杂质 5

英文化学名

3-Nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide

简化分子线性输入规范(SMILES)

O=S(C1=CC=C(N(N=O)CC2CCOCC2)C([N+]([O-])=O)=C1)(N)=O

分子式

C12H16N4O6S

分子量

344.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Nitroso Impurity 5 is chemically 3-Nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide. Venetoclax Nitroso Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Nitroso Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Venetoclax 杂质 34

英文化学名

1,1′-((((5,5,5”,5”-tetramethyl-3,3”,4,4”,5,5”,6,6”-octahydro-[1,1′:4′,1”-terphenyl]-2,2”-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide)

简化分子线性输入规范(SMILES)

CC1(C)CC(C2=CC=C(C3=C(CN4CCN(C5=CC=C(C(NS(C6=CC=C(NCC7CCOCC7)C([N+]([O-])=O)=C6)(=O)=O)=O)C(OC8=CC(C=CN9)=C9N=C8)=C5)CC4)CCC(C)(C)C3)C=C2)=C(CN%10CCN(C%11=CC=C(C(NS(C%12=CC=C(NCC%13CCOCC%13)C([N+]([O-])=O)=C%12)(=O)=O)=O)C(OC%14=CC%15=C(NC=C%15)N=C%14)=C%11)CC%10)CC1

分子式

C84H96N14O14S2

分子量

1589.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 34 is chemically 1,1′-((((5,5,5”,5”-tetramethyl-3,3”,4,4”,5,5”,6,6”-octahydro-[1,1′:4′,1”-terphenyl]-2,2”-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide). Venetoclax Impurity 34 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 34 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-34-cas-N/A/

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基本信息

CAS(化学文摘登记)号

2169699-41-4

英文名称

Venetoclax 杂质 37

英文化学名

Methyl 4-fluoro-2-((1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoate

简化分子线性输入规范(SMILES)

O=C(C(C=C1)=C(C=C1F)OC2=CN=C(N3CC(C=C4)=CC=C4OC)C(C=C3)=C2)OC

分子式

C23H19FN2O4

分子量

406.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 37 is chemically Methyl 4-fluoro-2-((1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoate. Venetoclax Impurity 37 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 37 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-37-cas-2169699-41-4/

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基本信息

CAS(化学文摘登记)号

2142574-09-0

英文名称

Venetoclax 杂质 16

英文化学名

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoic acid

简化分子线性输入规范(SMILES)

O=C(O)C1=CC=C(F)C=C1OC2=CN=C(NC=C3)C3=C2

分子式

C14H9FN2O3

分子量

272.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Venetoclax Impurity 16 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoic acid. Venetoclax Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/venetoclax-impurity-16-cas-2142574-09-0/

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