文章

基本信息

CAS(化学文摘登记)号

871700-30-0

英文名称

Trametinib 杂质 10

英文化学名

N’-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide

简化分子线性输入规范(SMILES)

CN(C)C=NC(N(C(C=CC(I)=C1)=C1F)C(N2C3CC3)=O)=CC2=O

分子式

C16H16FIN4O2

分子量

442.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Impurity 10 is chemically N’-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide. Trametinib Impurity 10 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Impurity 10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-impurity-10-cas-871700-30-0/

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基本信息

CAS(化学文摘登记)号

1383430-04-3

英文名称

Trametinib 杂质 6

英文化学名

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroperoxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

简化分子线性输入规范(SMILES)

O=C(C)NC1=CC=CC(N(C(N(C2CC2)C3=O)=O)C4=C3/C(N(C)C(C4(C)OO)=O)=N/C5=C(F)C=C(I)C=C5)=C1

分子式

C26H23FIN5O6

分子量

647.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Impurity 6 is chemically N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroperoxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide. Trametinib Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-impurity-6-cas-1383430-04-3/

相关产品

基本信息

CAS(化学文摘登记)号

871700-17-3

英文名称

Trametinib

英文化学名

N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

简化分子线性输入规范(SMILES)

CN1C(NC(C=CC(I)=C2)=C2F)=C(C(N3C4CC4)=O)C(N(C5=CC(NC(C)=O)=CC=C5)C3=O)=C(C)C1=O

分子式

C26H23FIN5O4

分子量

615.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib is chemically N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide. Trametinib is supplied with detailed characterization data compliant with regulatory guideline. Trametinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-cas-871700-17-3/

相关产品

871702-07-7 (Acetate salt) ; 871702-06-6 (sodium salt) ; 1187431-31-7 (hydrate) ; 1290629-63-8 (盐酸盐)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Trametinib Nitroso 杂质 2

英文化学名

N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)(nitroso)amino)phenyl)acetamide

简化分子线性输入规范(SMILES)

CC(NC1=CC=CC(N(C(C(C(N2C3CC3)=O)=C4N(C5=CC=C(I)C=C5F)C2=O)=C(C)C(N4C)=O)N=O)=C1)=O

分子式

C26H22FIN6O5

分子量

644.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Nitroso Impurity 2 is chemically N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)(nitroso)amino)phenyl)acetamide. Trametinib Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-nitroso-impurity-2-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-NitrosoTrametinib

英文化学名

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

简化分子线性输入规范(SMILES)

CC(NC1=CC=CC(N(C(C(C(N2C3CC3)=O)=C(N(C4=CC=C(I)C=C4F)N=O)N5C)=C(C)C5=O)C2=O)=C1)=O

分子式

C26H22FIN6O5

分子量

644.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-NitrosoTrametinib is chemically N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide. N-NitrosoTrametinib is supplied with detailed characterization data compliant with regulatory guideline. N-NitrosoTrametinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitrosotrametinib-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Trametinib 杂质 14

英文化学名

3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(2-methylquinolin-7-yl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

简化分子线性输入规范(SMILES)

O=C1N(C2=CC=C3C=CC(C)=NC3=C2)C(C(C(N1C4CC4)=O)=C(NC5=CC=C(I)C=C5F)N6C)=C(C)C6=O

分子式

C28H23FIN5O3

分子量

623.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Impurity 14 is chemically 3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(2-methylquinolin-7-yl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione. Trametinib Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-impurity-14-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Trametinib Nitroso 杂质 3

英文化学名

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)-N-methylnitrous amide

简化分子线性输入规范(SMILES)

O=NN(C1=CC=CC(N(C(C(C(N2C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C(C)C5=O)C2=O)=C1)C

分子式

C25H22FIN6O4

分子量

616.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Nitroso Impurity 3 is chemically N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)-N-methylnitrous amide. Trametinib Nitroso Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Nitroso Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-nitroso-impurity-3-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Trametinib 杂质 13

英文化学名

3-Cyclopropyl-1-(2-fluorophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

简化分子线性输入规范(SMILES)

O=C1N(C2=CC=CC=C2F)C3=C(C(O)=C(C)C(N3C)=O)C(N1C4CC4)=O

分子式

C18H16FN3O4

分子量

357.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Impurity 13 is chemically 3-Cyclopropyl-1-(2-fluorophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione. Trametinib Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-impurity-13-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Trametinib Nitroso 杂质 1

英文化学名

N-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-methylnitrous amide

简化分子线性输入规范(SMILES)

IC1=CC=C(N2C(N(N=O)C)=CC(N(C3CC3)C2=O)=O)C(F)=C1

分子式

C14H12FIN4O3

分子量

430.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib Nitroso Impurity 1 is chemically N-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-methylnitrous amide. Trametinib Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-nitroso-impurity-1-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

1620017-29-9

英文名称

Trametinib M7

英文化学名

1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

简化分子线性输入规范(SMILES)

O=C1N(C(C(C(N1C2CC2)=O)=C(N3C)NC4=CC=C(C=C4F)I)=C(C3=O)C)C5=CC=C(C(N)=C5)O

分子式

C24H21FIN5O4

分子量

589.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Trametinib M7 is chemically 1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione. It is also known as M7 Metabolite of Trametinib. Trametinib M7 is supplied with detailed characterization data compliant with regulatory guideline. Trametinib M7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trametinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/trametinib-m7-cas-1620017-29-9/

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