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Tofacitinib N-Oxide 杂质 3 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib N-Oxide 杂质 3

英文化学名

4-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 1-oxide

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](NC2=NC=[N+]([O-])C3=C2C=CN3)CN(C(CC#N)=O)CC1

分子式

C15H18N6O2

分子量

314.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib N-Oxide Impurity 3 is chemically 4-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 1-oxide. Tofacitinib N-Oxide Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib N-Oxide Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-n-oxide-impurity-3-cas-N/A/

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Tofacitinib 杂质 37 CAS号 773076-83-8

基本信息

CAS(化学文摘登记)号

773076-83-8

英文名称

Tofacitinib 杂质 37

英文化学名

Ethyl 2-cyano-4,4-dimethoxybutanoate

简化分子线性输入规范(SMILES)

O=C(OCC)C(C#N)CC(OC)OC

分子式

C9H15NO4

分子量

201.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 37 is chemically Ethyl 2-cyano-4,4-dimethoxybutanoate. Tofacitinib Impurity 37 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 37 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-37-cas-773076-83-8/

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Tofacitinib 杂质 48 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib 杂质 48

英文化学名

3-[(3R,4R)-4-methyl-3-[methyl( {7H-pyrrolo[2,3-d]pyrimidin-4-yl} )amino ]piperidin-1-yl]-3-oxopropanenitrile-N-Oxide

简化分子线性输入规范(SMILES)

[O-][N+]#CCC(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)=O

分子式

C16H20N6O2

分子量

328.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 48 is chemically 3-[(3R,4R)-4-methyl-3-[methyl( {7H-pyrrolo[2,3-d]pyrimidin-4-yl} )amino ]piperidin-1-yl]-3-oxopropanenitrile-N-Oxide. Tofacitinib Impurity 48 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 48 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-48-cas-N/A/

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Tofacitinib 杂质 45 CAS号 923036-25-3

基本信息

CAS(化学文摘登记)号

923036-25-3

英文名称

Tofacitinib 杂质 45

英文化学名

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

简化分子线性输入规范(SMILES)

CN([C@H]1CN(CC2=CC=CC=C2)CC[C@H]1C)C3=C4C(NC=C4)=NC(Cl)=N3

分子式

C20H24ClN5

分子量

369.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 45 is chemically N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Tofacitinib Impurity 45 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 45 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-45-cas-923036-25-3/

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Tofacitinib 杂质 56 CAS号 384337-90-0

基本信息

CAS(化学文摘登记)号

384337-90-0

英文名称

Tofacitinib 杂质 56

英文化学名

N-(1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

简化分子线性输入规范(SMILES)

CN(C(C(CC1)C)CN1CC2=CC=CC=C2)C3=C(C=CN4)C4=NC=N3

分子式

C20H25N5

分子量

335.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 56 is chemically N-(1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Tofacitinib Impurity 56 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 56 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-56-cas-384337-90-0/

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Tofacitinib Nitroso 杂质 2 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib Nitroso 杂质 2

英文化学名

N-((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)nitrous amide

简化分子线性输入规范(SMILES)

O=NN([C@H]1CN(C(CC#N)=O)CC[C@H]1C)C2=C3C(NC=C3)=NC=N2

分子式

C15H17N7O2

分子量

327.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Nitroso Impurity 2 is chemically N-((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)nitrous amide. Tofacitinib Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-nitroso-impurity-2-cas-N/A/

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Tofacitinib 杂质 52 CAS号 2407039-29-4

基本信息

CAS(化学文摘登记)号

2407039-29-4

英文名称

Tofacitinib 杂质 52

英文化学名

3-((3R,4R)-3-((7-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

简化分子线性输入规范(SMILES)

CN([C@H]([C@@H](CC1)C)CN1C(CC#N)=O)C2=C(C=CN3O)C3=NC=N2

分子式

C16H20N6O2

分子量

328.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 52 is chemically 3-((3R,4R)-3-((7-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile. Tofacitinib Impurity 52 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 52 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-52-cas-2407039-29-4/

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Tofacitinib 杂质 40 CAS号 477600-70-7

基本信息

CAS(化学文摘登记)号

477600-70-7

英文名称

Tofacitinib 杂质 40

英文化学名

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](NC)CN(CC2=CC=CC=C2)CC1

分子式

C14H22N2

分子量

218.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 40 is chemically (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine. Tofacitinib Impurity 40 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 40 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-40-cas-477600-70-7/

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1820713-38-9 (盐酸盐) ; 1062580-52-2 (dihydrochloride)

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Tofacitinib 杂质 47 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib 杂质 47

英文化学名

Butyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate

简化分子线性输入规范(SMILES)

O=C(OCCCC)CC(C(C#N)C(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)=O)=N

分子式

C23H31N7O3

分子量

453.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 47 is chemically Butyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate. Tofacitinib Impurity 47 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 47 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-47-cas-N/A/

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Tofacitinib 杂质 53 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib 杂质 53

英文化学名

3-((3R,4R)-3-((2-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

简化分子线性输入规范(SMILES)

N#CCC(N1C[C@H](N(C2=C3C(NC=C3)=NC(O)=N2)C)[C@H](C)CC1)=O

分子式

C16H20N6O2

分子量

328.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 53 is chemically 3-((3R,4R)-3-((2-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile. Tofacitinib Impurity 53 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 53 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-53-cas-N/A/

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