• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib-d3 Citrate

英文化学名

3-((3R,4R)-4-methyl-3-((methyl-d3)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](N(C2=NC=NC3=C2C=CN3)C([2H])([2H])[2H])CN(C(CC#N)=O)CC1.OC(CC(C(O)=O)(O)CC(O)=O)=O

分子式

C16H17N6OD3 : C6H8O7

分子量

315.4 : 192.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib-d3 Citrate is chemically 3-((3R,4R)-4-methyl-3-((methyl-d3)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate. Tofacitinib-d3 Citrate is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib-d3 Citrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价及关联信息

快速询价

邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-d3-citrate-cas-N/A/

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• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

1675248-19-7

英文名称

Tofacitinib Amide Impurity

英文化学名

1-​Piperidinepropanamid​e, 4-​methyl-​3-​(methyl-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​ylamino)​-​beta-​oxo-​, (3R,​4R)​-; (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanamide

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](N(C)C2=NC=NC3=C2C=CN3)CN(C(CC(N)=O)=O)CC1

分子式

C16H22N6O2

分子量

330.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Amide Impurity is chemically 1-​Piperidinepropanamid​e, 4-​methyl-​3-​(methyl-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​ylamino)​-​beta-​oxo-​, (3R,​4R)​-; (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanamide. Tofacitinib Amide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Amide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价及关联信息

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-amide-impurity-cas-1675248-19-7/

相关产品

• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib Impurity 3

英文化学名

2-Cyano-N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylacetamide

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](N(C)C(CC#N)=O)CN(C(CC#N)=O)CC1

分子式

C13H18N4O2

分子量

262.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 3 is chemically 2-Cyano-N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylacetamide. Tofacitinib Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价及关联信息

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-60-cas-N/A/

相关产品

• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

477600-74-1

英文名称

Tofacitinib Impurity M

英文化学名

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](N(C)C2=NC=NC3=C2C=CN3)CNCC1

分子式

C13H19N5

分子量

245.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity M is chemically N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Tofacitinib Impurity M is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity M can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价及关联信息

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-m-cas-477600-74-1/

相关产品

1260590-51-9 (HCl salt) : 1655430-59-3 (2HCl salt)

• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

1640971-87-4

英文名称

Tofacitinib Impurity 2

英文化学名

3-((3R,4R)-4-Methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile hydrochloride

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](NC)CN(C(CC#N)=O)CC1.[XHCl]

分子式

C10H17N3O : X(HCl)

分子量

195.3 : X(36.5)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 2 is chemically 3-((3R,4R)-4-Methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile hydrochloride. Tofacitinib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价及关联信息

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-59-cas-1640971-87-4/

相关产品

1629858-78-1 (free base)