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N-Nitroso Tofacitinib 杂质 5 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Tofacitinib 杂质 5

英文化学名

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide

简化分子线性输入规范(SMILES)

CN(N=O)[C@H]([C@H](C)CC1)CN1CC2=CC=CC=C2

分子式

C14H21N3O

分子量

247.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Tofacitinib Impurity 5 is chemically N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide. N-Nitroso Tofacitinib Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Tofacitinib Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-tofacitinib-impurity-5-cas-N/A/

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Tofacitinib Nitroso 杂质 4 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib Nitroso 杂质 4

英文化学名

3-((4R)-4-Methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-3-oxopropanenitrile

简化分子线性输入规范(SMILES)

N#CCC(C1CC(N(C)C2=C3C(N(N=O)C=C3)=NC=N2)[C@H](C)CC1)=O

分子式

C17H20N6O2

分子量

340.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Nitroso Impurity 4 is chemically 3-((4R)-4-Methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-3-oxopropanenitrile. Tofacitinib Nitroso Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Nitroso Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-nitroso-impurity-4-cas-N/A/

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Tofacitinib 杂质 46 CAS号 2102039-99-4

基本信息

CAS(化学文摘登记)号

2102039-99-4

英文名称

Tofacitinib 杂质 46

英文化学名

Ethyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-((2-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate

简化分子线性输入规范(SMILES)

O=C(OCC)CC(C(C#N)C(N1C[C@H](NC2=C3C(NC=C3)=NC(C)=N2)[C@H](C)CC1)=O)=N

分子式

C21H27N7O3

分子量

425.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 46 is chemically Ethyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-((2-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate. Tofacitinib Impurity 46 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 46 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-46-cas-2102039-99-4/

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Tofacitinib N-Oxide 杂质 6 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib N-Oxide 杂质 6

英文化学名

N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-amine

简化分子线性输入规范(SMILES)

O=NN1C=CC2=C(N([C@H]3CN(CC4=CC=CC=C4)CC[C@H]3C)C)N=CN=C21

分子式

C20H24N6O

分子量

364.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib N-Oxide Impurity 6 is chemically N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Tofacitinib N-Oxide Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib N-Oxide Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-n-oxide-impurity-6-cas-N/A/

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N-Nitroso Tofacitinib 杂质 6 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Tofacitinib 杂质 6

英文化学名

N-((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylnitrous amide

简化分子线性输入规范(SMILES)

O=C(N1CC[C@H]([C@H](C1)N(C)N=O)C)CC#N

分子式

C10H16N4O2

分子量

224.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Tofacitinib Impurity 6 is chemically N-((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylnitrous amide. N-Nitroso Tofacitinib Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Tofacitinib Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-tofacitinib-impurity-6-cas-N/A/

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Tofacitinib N-Oxide 杂质 5 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib N-Oxide 杂质 5

英文化学名

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-amine

简化分子线性输入规范(SMILES)

O=NN1C=CC2=C(N(C)[C@H]3CNCC[C@H]3C)N=CN=C21

分子式

C13H18N6O

分子量

274.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib N-Oxide Impurity 5 is chemically N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Tofacitinib N-Oxide Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib N-Oxide Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-n-oxide-impurity-5-cas-N/A/

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Tofacitinib N-Oxide 杂质 4 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib N-Oxide 杂质 4

英文化学名

3-((3R,4R)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](NC2=NC=NC3=C2C=CN3O)CN(C(CC#N)=O)CC1

分子式

C15H18N6O2

分子量

314.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib N-Oxide Impurity 4 is chemically 3-((3R,4R)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile. Tofacitinib N-Oxide Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib N-Oxide Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-n-oxide-impurity-4-cas-N/A/

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Tofacitinib 13C D2 15N CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib 13C D2 15N

英文化学名

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile-1-13C-2,2-d2-15N

简化分子线性输入规范(SMILES)

C[C@H]1[C@H](CN(CC1)C(C([2H])([2H])[13C]#[15N])=O)N(C2=NC=NC3=C2C=CN3)C

分子式

C1513CH18D2N515NO

分子量

316.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib 13C D2 15N is chemically 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile-1-13C-2,2-d2-15N. Tofacitinib 13C D2 15N is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib 13C D2 15N can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-13c-d2-15n-cas-N/A/

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Tofacitinib N-Oxide 杂质 2 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Tofacitinib N-Oxide 杂质 2

英文化学名

4-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 3-oxide

简化分子线性输入规范(SMILES)

C[C@H]1[C@@H](NC2=[N+]([O-])C=NC3=C2C=CN3)CN(C(CC#N)=O)CC1

分子式

C15H18N6O2

分子量

314.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib N-Oxide Impurity 2 is chemically 4-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 3-oxide. Tofacitinib N-Oxide Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib N-Oxide Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-n-oxide-impurity-2-cas-N/A/

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Tofacitinib 杂质 57 CAS号 2315287-12-6

基本信息

CAS(化学文摘登记)号

2315287-12-6

英文名称

Tofacitinib 杂质 57

英文化学名

3-Hydroxy-3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

简化分子线性输入规范(SMILES)

OC(CC#N)(N(CC[C@H]1C)C[C@@H]1N(C2=C(C=CN3)C3=NC=N2)C)C(C#N)C(N(CC[C@H]4C)C[C@@H]4N(C5=C(C=CN6)C6=NC=N5)C)=O

分子式

C32H40N12O2

分子量

624.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Tofacitinib Impurity 57 is chemically 3-Hydroxy-3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile. Tofacitinib Impurity 57 is supplied with detailed characterization data compliant with regulatory guideline. Tofacitinib Impurity 57 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tofacitinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/tofacitinib-impurity-57-cas-2315287-12-6/

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