文章

基本信息

CAS(化学文摘登记)号

13127-18-9

英文名称

Roxithromycin EP 杂质 C

英文化学名

Erythromycin 9-(E)-oxime (as per EP)

简化分子线性输入规范(SMILES)

C[C@H]([C@H]([C@](O)(C[C@H](/C1=N/O)C)C)O[C@@](O[C@H](C)C[C@@H]2N(C)C)([H])[C@@H]2O)[C@]([C@H](C(O[C@@H]([C@@](O)([C@H](O)[C@H]1C)C)CC)=O)C)([H])O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC

分子式

C37H68N2O13

分子量

749.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity C is chemically Erythromycin 9-(E)-oxime (as per EP). Roxithromycin EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-c-cas-13127-18-9/

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基本信息

CAS(化学文摘登记)号

114-07-8

英文名称

Roxithromycin EP 杂质 A

英文化学名

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione (as per EP)

简化分子线性输入规范(SMILES)

C[C@@H]([C@@H]([C@H](C(O[C@@H]1CC)=O)C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)[C@H]([C@](O)(C[C@H](C([C@@H]([C@@H](O)[C@@]1(O)C)C)=O)C)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O

分子式

C37H67NO13

分子量

733.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity A is chemically (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione (as per EP). It is also known as Erythromycin A (EP). Roxithromycin EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-a-cas-114-07-8/

相关产品

4501-00-2 (phophate salt) ; 7184-72-7 (硫酸盐)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso -N-Demethyl Roxithromycin

英文化学名

N-((2S,3R,4S,6R)-2-(((3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-methoxyethoxy)methoxy)imino)-3,5,7,9,11,13-hexamethyl-2-oxooxacyclotetradecan-6-yl)oxy)-3-hydroxy-6-methyltetrahydro-2H-pyran-4-yl)-N-methylnitrous amide

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@H]2[C@H](O)[C@@H](N(C)N=O)C[C@@H](C)O2)[C@](C)(O)C[C@H]/3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=NOCOCCOC

分子式

C40H73N3O16

分子量

852.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso -N-Demethyl Roxithromycin is chemically N-((2S,3R,4S,6R)-2-(((3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-methoxyethoxy)methoxy)imino)-3,5,7,9,11,13-hexamethyl-2-oxooxacyclotetradecan-6-yl)oxy)-3-hydroxy-6-methyltetrahydro-2H-pyran-4-yl)-N-methylnitrous amide. N-Nitroso -N-Demethyl Roxithromycin is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso -N-Demethyl Roxithromycin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

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https://www.chemwhat.com/n-nitroso-n-demethyl-roxithromycin-cas-N/A/

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基本信息

CAS(化学文摘登记)号

134931-00-3

英文名称

Roxithromycin EP 杂质 D

英文化学名

(9Z)-9-[O-[(2-Methoxyethoxy)methyl]oxime] Erythromycin

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O[C@@]1([H])C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@@]2([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@](C)(O)C[C@H]/3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=N/OCOCCOC

分子式

C41H76N2O15

分子量

837.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity D is chemically (9Z)-9-[O-[(2-Methoxyethoxy)methyl]oxime] Erythromycin. It is also known as (9Z)-Roxithromycin. Roxithromycin EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-d-cas-134931-00-3/

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基本信息

CAS(化学文摘登记)号

118267-18-8

英文名称

Roxithromycin EP 杂质 F

英文化学名

(9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime]-N-demethyl Erythromycin

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O[C@@]1([H])C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@@]2([H])[C@H](O)[C@@H](NC)C[C@@H](C)O2)[C@](C)(O)C[C@H]/3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=NOCOCCOC

分子式

C40H74N2O15

分子量

823.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity F is chemically (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime]-N-demethyl Erythromycin. It is also known as N-Demethyl Roxithromycin. Roxithromycin EP Impurity F is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity F can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-f-cas-118267-18-8/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Roxithromycin EP 杂质 K

英文化学名

(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-(hydroxymethoxy)ethoxy)methoxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

简化分子线性输入规范(SMILES)

OCOCCOCO/N=C([C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)O1)[C@H](C)C[C@@](C)(O)[C@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@](OC)(C)C3)[C@@H](C)C1=O

分子式

C41H76N2O16

分子量

853.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity K is chemically (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-(hydroxymethoxy)ethoxy)methoxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. Roxithromycin EP Impurity K is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity K can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-k-cas-N/A/

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基本信息

CAS(化学文摘登记)号

425365-66-8

英文名称

Roxithromycin EP 杂质 I

英文化学名

2′-0-[(2-methoxyethoxy) methyl] erythromycin 9-(E)-[0-[(2- methoxy ethoxy) methyl] oxime]

简化分子线性输入规范(SMILES)

O=C(O[C@H](CC)[C@@](C)(O)[C@H](O)[C@H]/1C)[C@H](C)[C@](O[C@@]2([H])C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)([H])[C@H](C)[C@@H](O[C@@]3([H])[C@H](OCOCCOC)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C1=N/OCOCCOC

分子式

C45H84N2O17

分子量

925.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity I is chemically 2′-0-[(2-methoxyethoxy) methyl] erythromycin 9-(E)-[0-[(2- methoxy ethoxy) methyl] oxime]. Roxithromycin EP Impurity I is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity I can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-i-cas-425365-66-8/

相关产品

基本信息

CAS(化学文摘登记)号

425365-65-7

英文名称

Roxithromycin EP 杂质 H

英文化学名

Erythromycin 9-(E)-[0-[[(2-methoxyethoxy) methoxy] methyl] oxime]

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@H]2[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@](C)(O)C[C@H]/3C)O[C@H](CC)[C@H](C)[C@H](O)[C@@H](C)C3=NOCOCCOC

分子式

C41H76N2O14

分子量

821.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity H is chemically Erythromycin 9-(E)-[0-[[(2-methoxyethoxy) methoxy] methyl] oxime]. Roxithromycin EP Impurity H is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/roxithromycin-ep-impurity-h-cas-425365-65-7/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

(Z)-Roxithromycin D7

英文化学名

(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,Z)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-(methoxy-d3)ethoxy-1,1,2,2-d4)methoxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@H]2[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@](C)(O)C[C@H]/3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=N/OCOC([2H])([2H])C([2H])([2H])OC([2H])([2H])[2H]

分子式

C41H69D7N2O15

分子量

844.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

(Z)-Roxithromycin D7 is chemically (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,Z)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-(methoxy-d3)ethoxy-1,1,2,2-d4)methoxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. (Z)-Roxithromycin D7 is supplied with detailed characterization data compliant with regulatory guideline. (Z)-Roxithromycin D7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/z-roxithromycin-d7-cas-N/A/

相关产品

134931-00-3 (Unlabeled)

基本信息

CAS(化学文摘登记)号

214902-82-6

英文名称

Roxithromycin EP 杂质 B

英文化学名

3-O-de(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)erythromycin 9-(E)-[O-[(2-methoxyethoxy)methyl]oxime] (as per EP)

简化分子线性输入规范(SMILES)

O=C([C@H](C)[C@@H](O)[C@H](C)[C@@H](O[C@@]1([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O1)[C@](C)(O)C[C@H]/2C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C2=NOCOCCOC

分子式

C33H62N2O12

分子量

678.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Roxithromycin EP Impurity B is chemically 3-O-de(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)erythromycin 9-(E)-[O-[(2-methoxyethoxy)methyl]oxime] (as per EP). Roxithromycin EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Roxithromycin EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxithromycin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

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