文章

基本信息

CAS(化学文摘登记)号

503610-43-3

英文名称

Rosuvastatin EP Impurity D

英文化学名

N-[4-(4-fluorophenyl)-5-[(1E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethen-1-yl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide (as per EP);N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]vinyl}-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide (as per USP)

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/[C@@H](O3)C[C@@H](O)CC3=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C22H26FN3O5S

分子量

463.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin EP Impurity D is chemically N-[4-(4-fluorophenyl)-5-[(1E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethen-1-yl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide (as per EP);N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]vinyl}-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide (as per USP). It is also known as Rosuvastatin Lactone. Rosuvastatin EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-ep-impurity-d-cas-503610-43-3/

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基本信息

CAS(化学文摘登记)号

289042-12-2

英文名称

Rosuvastatin EP Impurity F

英文化学名

1,1-dimethylethyl [(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate ;

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/[C@@H](OC(C)(C)O3)C[C@@H]3CC(OC(C)(C)C)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C29H40FN3O6S

分子量

577.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin EP Impurity F is chemically 1,1-dimethylethyl [(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate ; . It is also known as Rosuvastatin USP Related Compound C ; Rosuvastatin Acetonide t-Butyl Ester. Rosuvastatin EP Impurity F is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin EP Impurity F can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-ep-impurity-f-cas-289042-12-2/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Rosuvastatin EP Impurity J (Sodium Salt)

英文化学名

(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[[[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]ethenyl]sulfonyl](methyl)amino]-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid sodium salt

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/S(N(C)C3=NC(C4=CC=C(F)C=C4)=C(/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)C(C(C)C)=N3)(=O)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2.[Na+]

分子式

C38H43F2N6O8S2 : Na

分子量

813.9 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin EP Impurity J (Sodium Salt) is chemically (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[[[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]ethenyl]sulfonyl](methyl)amino]-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid sodium salt . Rosuvastatin EP Impurity J (Sodium Salt) is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin EP Impurity J (Sodium Salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-ep-impurity-j-sodium-salt-cas-N/A/

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基本信息

CAS(化学文摘登记)号

147118-36-3

英文名称

Rosuvastatin Hydroxymethyl Impurity

英文化学名

N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6- isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide ;

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(CO)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C16H20FN3O3S

分子量

353.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin Hydroxymethyl Impurity is chemically N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6- isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide ; . Rosuvastatin Hydroxymethyl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin Hydroxymethyl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-hydroxymethyl-impurity-cas-147118-36-3/

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基本信息

CAS(化学文摘登记)号

1422954-12-8

英文名称

Rosuvastatin EP Impurity K

英文化学名

(2xi,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-5-hydroxyhepta-2,6-dienoic acid (as per EP)

简化分子线性输入规范(SMILES)

CN(S(C)(=O)=O)C1=NC(C(C)C)=C(/C=C/[C@](O)([H])CC=CC(O)=O)C(C2=CC=C(F)C=C2)=N1

分子式

C22H26FN3O5S

分子量

463.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin EP Impurity K is chemically (2xi,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-5-hydroxyhepta-2,6-dienoic acid (as per EP). It is also known as 2Z,Dehydro Rosuvastatin. Rosuvastatin EP Impurity K is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin EP Impurity K can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-ep-impurity-k-cas-1422954-12-8/

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基本信息

CAS(化学文摘登记)号

2452383-22-9

英文名称

Rosuvastatin 2,3-Anhydro Acid Methyl Ester

英文化学名

(5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-hept-2,6-dienoic acid methyl ester

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/[C@@H](O)C/C=C/C(OC)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C23H28FN3O5S

分子量

477.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin 2,3-Anhydro Acid Methyl Ester is chemically (5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-hept-2,6-dienoic acid methyl ester. Rosuvastatin 2,3-Anhydro Acid Methyl Ester is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin 2,3-Anhydro Acid Methyl Ester can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-23-anhydro-acid-methyl-ester-cas-2452383-22-9/

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基本信息

CAS(化学文摘登记)号

854898-50-3

英文名称

Rosuvastatin (6S)-Isomer Hemicalcium Salt

英文化学名

calcium(I) (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate

简化分子线性输入规范(SMILES)

FC(C=C1)=CC2=C1C3=C(C[C@]2([H])[C@H](C[C@@H](O)CC([O-])=O)O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N3.[1/2Ca+]

分子式

C22H27FN3O6S : 1/2(Ca)

分子量

480.5 : 1/2(40.1)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin (6S)-Isomer Hemicalcium Salt is chemically calcium(I) (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate . It is also known as Rosuvastatin Dihydrobenzoquinazoline (6S)-Isomer. Rosuvastatin (6S)-Isomer Hemicalcium Salt is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin (6S)-Isomer Hemicalcium Salt can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-6s-isomer-hemicalcium-salt-cas-854898-50-3/

相关产品

854898-53-6 (free base)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Rosuvastatin 2,3,4,5-Dianhydro Acid

英文化学名

(6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-hept-2,4,6-trienoic acid

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/C=C/C=C/C(O)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C22H24FN3O4S

分子量

445.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin 2,3,4,5-Dianhydro Acid is chemically (6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-hept-2,4,6-trienoic acid. Rosuvastatin 2,3,4,5-Dianhydro Acid is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin 2,3,4,5-Dianhydro Acid can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-2345-dianhydro-acid-cas-N/A/

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基本信息

CAS(化学文摘登记)号

355806-00-7

英文名称

Rosuvastatin Acid t-Butyl Ester

英文化学名

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid t-butyl ester

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(/C=C/[C@@H](O)C[C@@H](O)CC(OC(C)(C)C)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2

分子式

C26H36FN3O6S

分子量

537.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin Acid t-Butyl Ester is chemically (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid t-butyl ester. It is also known as tert-Butyl rosuvastatin. Rosuvastatin Acid t-Butyl Ester is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin Acid t-Butyl Ester can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-acid-t-butyl-ester-cas-355806-00-7/

相关产品

1508253-62-0 (Ca salt)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Rosuvastatin EP Impurity E (Sodium Salt)

英文化学名

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl (methylsulfonyl)amino]-5-pyrimidinyl]-2-hydroxy-ethylsulfonyl)amino)-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid Sodium salt ;

简化分子线性输入规范(SMILES)

FC(C=C1)=CC=C1C2=C(C(O)CS(N(C)C3=NC(C4=CC=C(F)C=C4)=C(/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)C(C(C)C)=N3)(=O)=O)C(C(C)C)=NC(N(C)S(C)(=O)=O)=N2.[Na+]

分子式

C38H45F2N6O9S2 : Na

分子量

831.9 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Rosuvastatin EP Impurity E (Sodium Salt) is chemically (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl (methylsulfonyl)amino]-5-pyrimidinyl]-2-hydroxy-ethylsulfonyl)amino)-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid Sodium salt ; . It is also known as Rosuvastatin USP Related Compound B. Rosuvastatin EP Impurity E (Sodium Salt) is supplied with detailed characterization data compliant with regulatory guideline. Rosuvastatin EP Impurity E (Sodium Salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rosuvastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/rosuvastatin-ep-impurity-e-sodium-salt-cas-N/A/

相关产品

2226413-61-0 (free base)