文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib N-Oxide 杂质 2 (Hemihydrate)

英文化学名

1-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide sesquihydrate

简化分子线性输入规范(SMILES)

CN(C)C(C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(C=C4)=NC=C4[N+]5([O-])CCNCC5)=O.[1.5 H2O]

分子式

C23H30N8O2 : 1/2(H2O)

分子量

450.5 : 1/2(18.0)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib N-Oxide Impurity 2 (Hemihydrate) is chemically 1-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide sesquihydrate. Ribociclib N-Oxide Impurity 2 (Hemihydrate) is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib N-Oxide Impurity 2 (Hemihydrate) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-n-oxide-impurity-2-hemihydrate-cas-N/A/

相关产品

2470164-21-5 (游离碱)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 4

英文化学名

4-(4-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid

简化分子线性输入规范(SMILES)

OC(CCC(N1CCN(C2=CC=C(NC3=NC=C(C=C(C(N(C)C)=O)N4C5CCCC5)C4=N3)N=C2)CC1)=O)=O

分子式

C27H34N8O4

分子量

534.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 4 is chemically 4-(4-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid. Ribociclib Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-4-cas-N/A/

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基本信息

CAS(化学文摘登记)号

1374639-77-6

英文名称

Ribociclib Chloro Hydroxy 杂质

英文化学名

(2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol

简化分子线性输入规范(SMILES)

OCC1=CC2=CN=C(Cl)N=C2N1C3CCCC3

分子式

C12H14ClN3O

分子量

251.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Chloro Hydroxy Impurity is chemically (2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol. Ribociclib Chloro Hydroxy Impurity is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Chloro Hydroxy Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-chloro-hydroxy-impurity-cas-1374639-77-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib N,N-DiDesmethyl Metabolite

英文化学名

7-Cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

NC(C1=CC2=CN=C(NC3=CC=C(N4CCNCC4)C=N3)N=C2N1C5CCCC5)=O

分子式

C21H26N8O

分子量

406.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib N,N-DiDesmethyl Metabolite is chemically 7-Cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib N,N-DiDesmethyl Metabolite is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib N,N-DiDesmethyl Metabolite can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-nn-didesmethyl-metabolite-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib pyridine N-oxide

英文化学名

2-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide hydrochloride

简化分子线性输入规范(SMILES)

O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC4=CC=C(C=[N+]4[O-])N5CCNCC5.Cl

分子式

C23H30N8O2 : HCl

分子量

450.5 : 36.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib pyridine N-oxide is chemically 2-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide hydrochloride. Ribociclib pyridine N-oxide is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib pyridine N-oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-pyridine-n-oxide-cas-N/A/

相关产品

2069953-39-3 (游离碱)

基本信息

CAS(化学文摘登记)号

1328934-40-2

英文名称

Ribociclib-d6

英文化学名

7-Cyclopentyl-N,N-bis(methyl-d3)-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CC2=CN=C(NC3=CC=C(N4CCNCC4)C=N3)N=C2N1C5CCCC5)N(C([2H])([2H])[2H])C([2H])([2H])[2H]

分子式

C23H24D6N8O

分子量

440.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib-d6 is chemically 7-Cyclopentyl-N,N-bis(methyl-d3)-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib-d6 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib-d6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-d6-cas-1328934-40-2/

相关产品

基本信息

CAS(化学文摘登记)号

1211443-55-8

英文名称

Ribociclib 杂质 9

英文化学名

2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carbaldehyde

简化分子线性输入规范(SMILES)

O=CC1=CC2=CN=C(Cl)N=C2N1C3CCCC3

分子式

C12H12ClN3O

分子量

249.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 9 is chemically 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carbaldehyde. Ribociclib Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-9-cas-1211443-55-8/

相关产品

基本信息

CAS(化学文摘登记)号

1211443-61-6

英文名称

Ribociclib Chloro Amide 杂质

英文化学名

2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CC2=CN=C(Cl)N=C2N1C3CCCC3)N(C)C

分子式

C14H17ClN4O

分子量

292.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Chloro Amide Impurity is chemically 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib Chloro Amide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Chloro Amide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-chloro-amide-impurity-cas-1211443-61-6/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Formyl Ribociclib (盐酸盐)

英文化学名

7-Cyclopentyl-2-((5-(4-formylpiperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride

简化分子线性输入规范(SMILES)

[H]C(N1CCN(C2=CN=C(NC3=NC=C4C(N(C5CCCC5)C(C(N(C)C)=O)=C4)=N3)C=C2)CC1)=O.Cl

分子式

C24H30N8O2 : HCl

分子量

462.6 : 36.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Formyl Ribociclib (HCl salt) is chemically 7-Cyclopentyl-2-((5-(4-formylpiperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride. N-Formyl Ribociclib (HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. N-Formyl Ribociclib (HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-formyl-ribociclib-hcl-salt-cas-N/A/

相关产品

2460732-08-3 (游离碱)

基本信息

CAS(化学文摘登记)号

2514753-27-4

英文名称

Ribociclib N-Oxide 杂质 1

英文化学名

7-Cyclopentyl-6-(dimethylcarbamoyl)-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 7-oxide

简化分子线性输入规范(SMILES)

CN(C)C(C([N+]1([O-])C2CCCC2)=CC(C1=N3)=CN=C3NC(C=C4)=NC=C4N5CCNCC5)=O

分子式

C23H30N8O2

分子量

450.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ribociclib N-Oxide Impurity 1 is chemically 7-Cyclopentyl-6-(dimethylcarbamoyl)-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine 7-oxide. Ribociclib N-Oxide Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib N-Oxide Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-n-oxide-impurity-1-cas-2514753-27-4/

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