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Ribociclib 杂质 48 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 48

英文化学名

Di-tert-butyl 2,2′-((((6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridine-2,4-diyl)bis(azanediyl))bis(pyridine-6,3-diyl))bis(piperazine-4,1-diyl))bis(2-oxoacetate)

简化分子线性输入规范(SMILES)

O=C(N(C)C)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC(NC5=NC=C(C=C5)N6CCN(CC6)C(C(OC(C)(C)C)=O)=O)=CC(NC7=NC=C(C=C7)N8CCN(CC8)C(C(OC(C)(C)C)=O)=O)=C4

分子式

C49H62N14O7

分子量

959.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 48 is chemically Di-tert-butyl 2,2′-((((6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridine-2,4-diyl)bis(azanediyl))bis(pyridine-6,3-diyl))bis(piperazine-4,1-diyl))bis(2-oxoacetate). Ribociclib Impurity 48 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 48 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-48-cas-N/A/

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Ribociclib Amine 杂质 CAS号 1331847-17-6

基本信息

CAS(化学文摘登记)号

1331847-17-6

英文名称

Ribociclib Amine 杂质

英文化学名

2-Amino-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

NC1=NC=C2C(N(C3CCCC3)C(C(N(C)C)=O)=C2)=N1

分子式

C14H19N5O

分子量

273.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Amine Impurity is chemically 2-Amino-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib Amine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Amine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-amine-impurity-cas-1331847-17-6/

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Ribociclib 杂质 17 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 17

英文化学名

Methyl 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

简化分子线性输入规范(SMILES)

O=C(OC)C1=CC2=CN=C(NC3=CC=C(N4CCNCC4)C=N3)N=C2N1C5CCCC5

分子式

C22H27N7O2

分子量

421.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 17 is chemically Methyl 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate. Ribociclib Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-17-cas-N/A/

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Ribociclib 杂质 46 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 46

英文化学名

Tert-butyl 4-(2-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate

简化分子线性输入规范(SMILES)

O=C(N(C)C)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=CC=C4N5CCN(CC5)C(OC(C)(C)C)=O

分子式

C28H38N8O3

分子量

534.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 46 is chemically Tert-butyl 4-(2-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Ribociclib Impurity 46 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 46 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-46-cas-N/A/

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Ribociclib 杂质 40 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 40

英文化学名

Tert-butyl 2-(4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoacetate

简化分子线性输入规范(SMILES)

O=C(OC(C)(C)C)C(N1CCN(C2=CC=C(NC3=NC=C4C(N(C5CCCC5)C(C(N(C)C)=O)=C4)=N3)N=C2)CC1)=O

分子式

C29H38N8O4

分子量

562.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 40 is chemically Tert-butyl 2-(4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoacetate. Ribociclib Impurity 40 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 40 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-40-cas-N/A/

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Ribociclib Nitroso 杂质 1 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib Nitroso 杂质 1

英文化学名

7-Cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CC2=CN=C(NC3=CC=C(N4CCN(N=O)CC4)C=N3)N=C2N1C5CCCC5)N(C)C

分子式

C23H29N9O2

分子量

463.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Nitroso Impurity 1 is chemically 7-Cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-nitroso-impurity-1-cas-N/A/

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Ribociclib 杂质 43 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 43

英文化学名

Tert-butyl 2-(4-(6-((6-((2-chloro-5-(3-hydroxyprop-1-yn-1-yl)pyrimidin-4-yl)(cyclopentyl)carbamoyl)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoacetate

简化分子线性输入规范(SMILES)

O=C(OC(C)(C)C)C(N1CCN(C2=CC=C(NC3=NC=C4C(N(C5CCCC5)C(C(N(C6=NC(Cl)=NC=C6C#CCO)C7CCCC7)=O)=C4)=N3)N=C2)CC1)=O

分子式

C39H45ClN10O5

分子量

769.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 43 is chemically Tert-butyl 2-(4-(6-((6-((2-chloro-5-(3-hydroxyprop-1-yn-1-yl)pyrimidin-4-yl)(cyclopentyl)carbamoyl)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoacetate. Ribociclib Impurity 43 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 43 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-43-cas-N/A/

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Ribociclib 杂质 44 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ribociclib 杂质 44

英文化学名

3-(2-Chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-yl 2-((5-(4-(2-(tert-butoxy)-2-oxoacetyl)piperazin-1-yl)pyridin-2-yl)amino)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

简化分子线性输入规范(SMILES)

O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(C(C(OC(C)(C)C)=O)=O)CC4)C=C3)N=C2N1C5CCCC5)OCC#CC6=CN=C(Cl)N=C6NC7CCCC7

分子式

C39H45ClN10O5

分子量

769.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 44 is chemically 3-(2-Chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-yl 2-((5-(4-(2-(tert-butoxy)-2-oxoacetyl)piperazin-1-yl)pyridin-2-yl)amino)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate. Ribociclib Impurity 44 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 44 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-44-cas-N/A/

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N-Nitroso Ribociclib 杂质 5 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Ribociclib 杂质 5

英文化学名

N-(2-Chloro-5-(3-hydroxyprop-1-yn-1-yl)pyrimidin-4-yl)-N-cyclopentylnitrous amide

简化分子线性输入规范(SMILES)

ClC1=NC=C(C#CCO)C(N(C2CCCC2)N=O)=N1

分子式

C12H13ClN4O2

分子量

280.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Ribociclib Impurity 5 is chemically N-(2-Chloro-5-(3-hydroxyprop-1-yn-1-yl)pyrimidin-4-yl)-N-cyclopentylnitrous amide. N-Nitroso Ribociclib Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Ribociclib Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-ribociclib-impurity-5-cas-N/A/

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Ribociclib 杂质 32 CAS号 1211444-14-2

基本信息

CAS(化学文摘登记)号

1211444-14-2

英文名称

Ribociclib 杂质 32

英文化学名

2-Chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CC2=CN=C(Cl)N=C2N1C3CCCC3)NC

分子式

C13H15ClN4O

分子量

278.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ribociclib Impurity 32 is chemically 2-Chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide. Ribociclib Impurity 32 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 32 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ribociclib-impurity-32-cas-1211444-14-2/

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