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Regorafenib FP 杂质 A CAS号 2514957-39-0

基本信息

CAS(化学文摘登记)号

2514957-39-0

英文名称

Regorafenib FP 杂质 A

英文化学名

Ethyl [2-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]oxy]phenyl]carbamate

简化分子线性输入规范(SMILES)

O=C(OCC)NC1=CC=C(OC2=CC(C(NC)=O)=NC=C2)C=C1F

分子式

C16H16FN3O4

分子量

333.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib FP Impurity A is chemically Ethyl [2-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]oxy]phenyl]carbamate. Regorafenib FP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib FP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib—. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-fp-impurity-a-cas-2514957-39-0/

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Regorafenib N-Oxide D3 CAS号 1333489-03-4

基本信息

CAS(化学文摘登记)号

1333489-03-4

英文名称

Regorafenib N-Oxide D3

英文化学名

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-((methyl-d3)carbamoyl)pyridine 1-oxide

简化分子线性输入规范(SMILES)

FC1=C(NC(NC2=CC(C(F)(F)F)=C(Cl)C=C2)=O)C=CC(OC(C=C3C(NC([2H])([2H])[2H])=O)=CC=[N]3=O)=C1

分子式

C21H12D3ClF4N4O4

分子量

501.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib N-Oxide D3 is chemically 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-((methyl-d3)carbamoyl)pyridine 1-oxide. Regorafenib N-Oxide D3 is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib N-Oxide D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-n-oxide-d3-cas-1333489-03-4/

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N-Desmethyl Regorafenib N-Oxide CAS号 835621-12-0

基本信息

CAS(化学文摘登记)号

835621-12-0

英文名称

N-Desmethyl Regorafenib N-Oxide

英文化学名

2-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide

简化分子线性输入规范(SMILES)

O=C(C1=CC(OC2=CC=C(C(F)=C2)NC(NC3=CC=C(C(C(F)(F)F)=C3)Cl)=O)=CC=[N+]1[O-])N

分子式

C20H13ClF4N4O4

分子量

484.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Desmethyl Regorafenib N-Oxide is chemically 2-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide. N-Desmethyl Regorafenib N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. N-Desmethyl Regorafenib N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-desmethyl-regorafenib-n-oxide-cas-835621-12-0/

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Regorafenib EP 杂质 E CAS号 2098799-13-2

基本信息

CAS(化学文摘登记)号

2098799-13-2

英文名称

Regorafenib EP 杂质 E

英文化学名

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)-N-methylpicolinamide

简化分子线性输入规范(SMILES)

CNC(C1=CC(OC2=CC=C(C(OC3=CC(F)=C(NC(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O)C=C3)=C2)NC(NC5=CC=C(Cl)C(C(F)(F)F)=C5)=O)=CC=N1)=O

分子式

C35H23Cl2F7N6O5

分子量

811.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib EP Impurity E is chemically 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)-N-methylpicolinamide. Regorafenib EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-ep-impuritye-cas-2098799-13-2/

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Regorafenib EP 杂质 D CAS号 2438857-80-6

基本信息

CAS(化学文摘登记)号

2438857-80-6

英文名称

Regorafenib EP 杂质 D

英文化学名

33,72-difluoro-N,N′-dimethyl-5-oxo-2,8-dioxa-4,6-diaza-1(4),9(4)-dipyridina-3(1,4),7(1,4)-dibenzenanonaphane-12,92-dicarboxamide

简化分子线性输入规范(SMILES)

O=C(NC)C1=NC=CC(OC2=CC(F)=C(NC(NC3=C(F)C=C(OC4=CC(C(NC)=O)=NC=C4)C=C3)=O)C=C2)=C1

分子式

C27H22F2N6O5

分子量

548.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib EP Impurity D is chemically 33,72-difluoro-N,N′-dimethyl-5-oxo-2,8-dioxa-4,6-diaza-1(4),9(4)-dipyridina-3(1,4),7(1,4)-dibenzenanonaphane-12,92-dicarboxamide. Regorafenib EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib—. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-ep-impurityd-cas-2438857-80-6/

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Regorafenib D3 CAS号 1255386-16-3

基本信息

CAS(化学文摘登记)号

1255386-16-3

英文名称

Regorafenib D3

英文化学名

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(methyl-d3)picolinamide

简化分子线性输入规范(SMILES)

FC1=C(NC(NC2=CC(C(F)(F)F)=C(Cl)C=C2)=O)C=CC(OC3=CC=NC(C(NC([2H])([2H])[2H])=O)=C3)=C1

分子式

C21H12D3ClF4N4O3

分子量

485.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib D3 is chemically 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(methyl-d3)picolinamide. Regorafenib D3 is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-d3-cas-1255386-16-3/

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Regorafenib EP 杂质 A CAS号 757251-39-1

基本信息

CAS(化学文摘登记)号

757251-39-1

英文名称

Regorafenib EP 杂质 A

英文化学名

4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=NC=CC(OC2=CC=C(N)C(F)=C2)=C1)NC

分子式

C13H12FN3O2

分子量

261.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib EP Impurity A is chemically 4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide. Regorafenib EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib—. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-ep-impuritya-cas-757251-39-1/

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Regorafenib EP 杂质 C CAS号 1855006-12-0

基本信息

CAS(化学文摘登记)号

1855006-12-0

英文名称

Regorafenib EP 杂质 C

英文化学名

4-[3-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=NC=CC(OC2=CC=C(NC3=CC(C(NC)=O)=NC=C3)C(F)=C2)=C1)NC

分子式

C20H18FN5O3

分子量

395.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Regorafenib EP Impurity C is chemically 4-[3-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide. Regorafenib EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Regorafenib EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Regorafenib—. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/regorafenib-ep-impurityc-cas-1855006-12-0/

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