文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 5

英文化学名

((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl isobutyrate

简化分子线性输入规范(SMILES)

FC1=CC(F)=C([C@@]2(CN3C=NC=N3)C[C@H](COC(C(C)C)=O)CO2)C=C1

分子式

C18H21F2N3O3

分子量

365.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 5 is chemically ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl isobutyrate. Posaconazole Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 8

英文化学名

2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide

简化分子线性输入规范(SMILES)

OC1=CC=C(N2CCN(C3=CC=C(NC(NN[C@@H](CC)[C@H](C)OCC4=CC=CC=C4)=O)C=C3)CC2)C=C1

分子式

C29H37N5O3

分子量

503.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 8 is chemically 2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide. Posaconazole Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-8-cas-N/A/

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基本信息

CAS(化学文摘登记)号

1388148-30-8

英文名称

Posaconazole Impurity 22

英文化学名

D-​threo-​Pentitol, 2,​5-​anhydro-​1,​3,​4-​trideoxy-​2-​C-​(2,​4-​difluorophenyl)​-​4-​[[[4-​[4-​[1-​[(1S,​2S)​-​1-​ethyl-​2-​hydroxypropyl]​-​1,​5-​dihydro-​5-​oxo-​4H-​1,​2,​4-​triazol-​4-​yl]​phenyl]​-​2,​3,​4,​5-​tetrahydro-​1H-​1,​4-​benzodiazepin-​7-​yl]​oxy]​methyl]​-​1-​(1H-​1,​2,​4-​triazol-​1-​yl)​-;

简化分子线性输入规范(SMILES)

O=C(N([C@@H](CC)[C@@H](O)C)N=C1)N1C2=CC=C(N3CCNC4=CC=C(OC[C@H]5O[C@@](C6=C(F)C=C(F)C=C6)(CN7C=NC=N7)OC5)C=C4C3)C=C2

分子式

C36H40F2N8O4

分子量

686.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 22 is chemically D-​threo-​Pentitol, 2,​5-​anhydro-​1,​3,​4-​trideoxy-​2-​C-​(2,​4-​difluorophenyl)​-​4-​[[[4-​[4-​[1-​[(1S,​2S)​-​1-​ethyl-​2-​hydroxypropyl]​-​1,​5-​dihydro-​5-​oxo-​4H-​1,​2,​4-​triazol-​4-​yl]​phenyl]​-​2,​3,​4,​5-​tetrahydro-​1H-​1,​4-​benzodiazepin-​7-​yl]​oxy]​methyl]​-​1-​(1H-​1,​2,​4-​triazol-​1-​yl)​-;. Posaconazole Impurity 22 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 22 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-22-cas-1388148-30-8/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 23

英文化学名

2-((2R,3R)-2-hydroxypentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one Dihydrochloride

简化分子线性输入规范(SMILES)

O=C(N([C@H](CC)[C@H](O)C)N=C1)N1C2=CC=C(N3CCN(C4=CC=C(O)C=C4)CC3)C=C2.[. 2HCl]

分子式

C23H29N5O3 : 2(HCl)

分子量

423.52 : 2(36.5)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 23 is chemically 2-((2R,3R)-2-hydroxypentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one Dihydrochloride . Posaconazole Impurity 23 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 23 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-23-cas-N/A/

相关产品

2243785-84-2 (Free base)

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 41

英文化学名

4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide

简化分子线性输入规范(SMILES)

O=C(N([C@H](CC)[C@@H](O)C)N=C1)N1C2=CC=C([N+]3([O-])CCN(C4=CC=C(OC[C@@H]5CO[C@@](CN6N=CN=C6)(C7=CC=C(F)C=C7F)C5)C=C4)CC3)C=C2

分子式

C37H42F2N8O5

分子量

716.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 41 is chemically 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide. Posaconazole Impurity 41 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 41 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-41-cas-N/A/

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基本信息

CAS(化学文摘登记)号

213381-05-6

英文名称

Posaconazole Diastereoisomer 2 (R,S,R,R)

英文化学名

4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6[C@H](CC)[C@H](O)C)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7

分子式

C37H42F2N8O4

分子量

700.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Diastereoisomer 2 (R,S,R,R) is chemically 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Posaconazole Diastereoisomer 2 (R,S,R,R) is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Diastereoisomer 2 (R,S,R,R) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-diastereoisomer-2-rsrr-cas-213381-05-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 6

英文化学名

1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-2-formyl-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide

简化分子线性输入规范(SMILES)

OC1=CC=C(N2CCN(C3=CC=C(NC(N([C@@H](CC)[C@@H](OCC4=CC=CC=C4)C)NC=O)=O)C=C3)CC2)C=C1

分子式

C30H37N5O4

分子量

531.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 6 is chemically 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-2-formyl-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide. Posaconazole Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-6-cas-N/A/

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基本信息

CAS(化学文摘登记)号

345217-02-9

英文名称

Posaconazole Impurity 7

英文化学名

1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide

简化分子线性输入规范(SMILES)

OC1=CC=C(N2CCN(C3=CC=C(NC(N([C@@H](CC)[C@@H](OCC4=CC=CC=C4)C)N)=O)C=C3)CC2)C=C1

分子式

C29H37N5O3

分子量

503.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 7 is chemically 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide. Posaconazole Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-7-cas-345217-02-9/

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基本信息

CAS(化学文摘登记)号

175712-02-4

英文名称

Posaconazole Impurity 21

英文化学名

((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate

简化分子线性输入规范(SMILES)

FC1=CC(F)=C([C@@]2(CN3C=NC=N3)C[C@H](COS(=O)(C4=CC=C(Cl)C=C4)=O)CO2)C=C1

分子式

C20H18ClF2N3O4S

分子量

469.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 21 is chemically ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate. Posaconazole Impurity 21 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 21 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-21-cas-175712-02-4/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole Impurity 37

英文化学名

((2S,3R)-2-(benzyloxy)pentan-3-yl)hydrazine (2S,3S)-2,3-bis(benzoyloxy)succinate

简化分子线性输入规范(SMILES)

O=C(O[C@@H]([C@@H](C(O)=O)OC(C1=CC=CC=C1)=O)C(O)=O)C2=CC=CC=C2.C[C@@H]([C@H](NN)CC)OCC3=CC=CC=C3

分子式

C18H14O8 : C12H20N2O

分子量

358.3 : 208.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 37 is chemically ((2S,3R)-2-(benzyloxy)pentan-3-yl)hydrazine (2S,3S)-2,3-bis(benzoyloxy)succinate. Posaconazole Impurity 37 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 37 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-37-cas-N/A/

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