文章

基本信息

CAS(化学文摘登记)号

184177-81-9

英文名称

Posaconazole 杂质 32

英文化学名

phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

简化分子线性输入规范(SMILES)

OC(C=C1)=CC=C1N(CC2)CCN2C3=CC=C(NC(OC4=CC=CC=C4)=O)C=C3

分子式

C23H23N3O3

分子量

389.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 32 is chemically phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate. Posaconazole Impurity 32 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 32 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-32-cas-184177-81-9/

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基本信息

CAS(化学文摘登记)号

161532-65-6

英文名称

Deshydroxy Posaconazole

英文化学名

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(pentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(CC)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7

分子式

C37H42F2N8O3

分子量

684.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Deshydroxy Posaconazole is chemically 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(pentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Deshydroxy Posaconazole is supplied with detailed characterization data compliant with regulatory guideline. Deshydroxy Posaconazole can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/deshydroxy-posaconazole-cas-161532-65-6/

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基本信息

CAS(化学文摘登记)号

159811-30-0

英文名称

Posaconazole Diastereoisomer 相关化合物 1

英文化学名

((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@@H](CO[S](=O)(C3=CC=C(C)C=C3)=O)CO2)CN4C=NC=N4

分子式

C21H21F2N3O4S

分子量

449.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Diastereoisomer Related Compound 1 is chemically ((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate. Posaconazole Diastereoisomer Related Compound 1 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Diastereoisomer Related Compound 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-diastereoisomer-related-compound-1-cas-159811-30-0/

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基本信息

CAS(化学文摘登记)号

357189-97-0

英文名称

Posaconazole 杂质 D

英文化学名

N-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)formamide

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@H](COC3=CC=C(NC=O)C=C3)CO2)CN4C=NC=N4

分子式

C21H20F2N4O3

分子量

414.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity D is chemically N-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)formamide. Posaconazole Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-d-cas-357189-97-0/

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基本信息

CAS(化学文摘登记)号

1488301-79-6

英文名称

Posaconazole Succinyl Ester

英文化学名

4-(((2S,3S)-3-(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)pentan-2-yl)oxy)-4-oxobutanoic acid

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6[C@](CC)([H])[C@H](C)OC(CCC(O)=O)=O)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7

分子式

C41H46F2N8O7

分子量

800.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Succinyl Ester is chemically 4-(((2S,3S)-3-(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)pentan-2-yl)oxy)-4-oxobutanoic acid. Posaconazole Succinyl Ester is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Succinyl Ester can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-succinyl-ester-cas-1488301-79-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole 杂质 28

英文化学名

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2-fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

简化分子线性输入规范(SMILES)

O=C(N([C@H](CC)[C@@H](O)C)N=C1)N1C2=CC=C(N3CCN(C4=CC=C(OC[C@@H]5CO[C@@](CN6N=CN=C6)(C7=CC=C(N8C=NC=N8)C=C7F)C5)C=C4)CC3)C=C2

分子式

C39H44FN11O4

分子量

749.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 28 is chemically 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2-fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Posaconazole Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-28-cas-N/A/

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基本信息

CAS(化学文摘登记)号

2243785-81-9

英文名称

Posaconazole 杂质 35

英文化学名

N’-((2R,3S)-2-(benzyloxy)pentan-3-yl)formohydrazide

简化分子线性输入规范(SMILES)

C[C@H]([C@@H](NNC=O)CC)OCC1=CC=CC=C1

分子式

C13H20N2O2

分子量

236.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 35 is chemically N’-((2R,3S)-2-(benzyloxy)pentan-3-yl)formohydrazide. Posaconazole Impurity 35 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 35 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-35-cas-2243785-81-9/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Posaconazole 杂质 42

英文化学名

1-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide 2,2,2-trifluoroacetate

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)[C@]2(C[C@H](COC3=CC=C([N]4(CCN(C5=CC=C(N(C=NN6[C@@H](CC)[C@@H](O)C)C6=O)C=C5)CC4)=O)C=C3)CO2)CN7C=NC=N7.OC(C(F)(F)F)=O

分子式

C37H42F2N8O5 : C2HF3O2

分子量

716.8 : 114.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 42 is chemically 1-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide 2,2,2-trifluoroacetate. Posaconazole Impurity 42 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 42 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-42-cas-N/A/

相关产品

1902954-05-5 (free base)

基本信息

CAS(化学文摘登记)号

1246391-73-0

英文名称

Posaconazole Diastereoisomer 9 (S,S,S,S)

英文化学名

4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

简化分子线性输入规范(SMILES)

O=C1N([C@@H](CC)[C@@H](O)C)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@H]5CO[C@@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C=C4)CC3)C=C2

分子式

C37H42F2N8O4

分子量

700.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Diastereoisomer 9 (S,S,S,S) is chemically 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Posaconazole Diastereoisomer 9 (S,S,S,S) is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Diastereoisomer 9 (S,S,S,S) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-diastereoisomer-9-ssss-cas-1246391-73-0/

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基本信息

CAS(化学文摘登记)号

149882-18-8

英文名称

Posaconazole Impurity 17

英文化学名

((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol

简化分子线性输入规范(SMILES)

FC1=CC(F)=C([C@]2(CN3C=NC=N3)C[C@@H](CO)CO2)C=C1

分子式

C14H15F2N3O2

分子量

295.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Posaconazole Impurity 17 is chemically ((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol. Posaconazole Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Posaconazole Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Posaconazole. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/posaconazole-impurity-17-cas-149882-18-8/

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