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Ponatinib-D8 CAS号 1562993-37-6

基本信息

CAS(化学文摘登记)号

1562993-37-6

英文名称

Ponatinib-D8

英文化学名

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)-3-(trifluoromethyl)phenyl)benzamide

简化分子线性输入规范(SMILES)

CC(C(C#CC1=CN=C2N1N=CC=C2)=C3)=CC=C3C(NC(C=C4)=CC(C(F)(F)F)=C4CN(C([2H])([2H])C5([2H])[2H])C([2H])([2H])C([2H])([2H])N5C)=O

分子式

C29H19D8F3N6O

分子量

540.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib-D8 is chemically 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)-3-(trifluoromethyl)phenyl)benzamide. Ponatinib-D8 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib-D8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-d8-cas-1562993-37-6/

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Ponatinib 杂质 6 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ponatinib 杂质 6

英文化学名

Benzyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate

简化分子线性输入规范(SMILES)

O=C(OCC1=CC=CC=C1)C2=CC=C(C)C(C#CC3=CN=C4C=CC=NN43)=C2

分子式

C23H17N3O2

分子量

367.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 6 is chemically Benzyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate. Ponatinib Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-6-cas-N/A/

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Ponatinib 杂质 1 CAS号 694499-26-8

基本信息

CAS(化学文摘登记)号

694499-26-8

英文名称

Ponatinib 杂质 1

英文化学名

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

简化分子线性输入规范(SMILES)

NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1

分子式

C13H18F3N3

分子量

273.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 1 is chemically 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline. Ponatinib Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-1-cas-694499-26-8/

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Ponatinib 杂质 7 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ponatinib 杂质 7

英文化学名

N-Benzyl-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

简化分子线性输入规范(SMILES)

FC(C1=CC(NCC2=CC=CC=C2)=CC=C1CN3CCN(C)CC3)(F)F

分子式

C20H24F3N3

分子量

363.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 7 is chemically N-Benzyl-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline. Ponatinib Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-7-cas-N/A/

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Ponatinib N-Oxide CAS号 2227480-51-3

基本信息

CAS(化学文摘登记)号

2227480-51-3

英文名称

Ponatinib N-Oxide

英文化学名

4-(4-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-1-methylpiperazine 1-oxide

简化分子线性输入规范(SMILES)

C[N+]1([O-])CCN(CC2=CC=C(NC(C3=CC=C(C)C(C#CC4=CN=C5C=CC=NN54)=C3)=O)C=C2C(F)(F)F)CC1

分子式

C29H27F3N6O2

分子量

548.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib N-Oxide is chemically 4-(4-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-1-methylpiperazine 1-oxide. Ponatinib N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-n-oxide-cas-2227480-51-3/

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Ponatinib N-beta-D-Glucuronide CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ponatinib N-beta-D-Glucuronide

英文化学名

1-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-4-(4-(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-1-methylpiperazin-1-ium bromide

简化分子线性输入规范(SMILES)

C[N+]1([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2)CCN(CC3=CC=C(NC(C4=CC=C(C)C(C#CC5=CN=C6C=CC=NN65)=C4)=O)C=C3C(F)(F)F)CC1.[Br-]

分子式

C35H36F3N6O7 : Br

分子量

789.6 : 79.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib N-beta-D-Glucuronide is chemically 1-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-4-(4-(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-1-methylpiperazin-1-ium bromide. Ponatinib N-beta-D-Glucuronide is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib N-beta-D-Glucuronide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-n-beta-d-glucuronide-cas-N/A/

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Ponatinib 杂质 4 CAS号 1356385-96-0

基本信息

CAS(化学文摘登记)号

1356385-96-0

英文名称

Ponatinib 杂质 4

英文化学名

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate

简化分子线性输入规范(SMILES)

O=C(OC)C1=CC=C(C)C(C#CC2=CN=C3C=CC=NN32)=C1

分子式

C17H13N3O2

分子量

291.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 4 is chemically Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate. Ponatinib Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-4-cas-1356385-96-0/

相关产品

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Ponatinib 杂质 5 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ponatinib 杂质 5

英文化学名

3,5-Bis(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

简化分子线性输入规范(SMILES)

O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)C3=CC(C#CC4=CN=C5C=CC=NN54)=C(C)C(C#CC6=CN=C7C=CC=NN76)=C3

分子式

C37H30F3N9O

分子量

673.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 5 is chemically 3,5-Bis(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide. Ponatinib Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-5-cas-N/A/

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Ponatinib 杂质 2 CAS号 1300690-48-5

基本信息

CAS(化学文摘登记)号

1300690-48-5

英文名称

Ponatinib 杂质 2

英文化学名

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid

简化分子线性输入规范(SMILES)

O=C(O)C1=CC=C(C)C(C#CC2=CN=C3C=CC=NN32)=C1

分子式

C16H11N3O2

分子量

277.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib Impurity 2 is chemically 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid. Ponatinib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-impurity-2-cas-1300690-48-5/

相关产品

2306904-72-1 (盐酸盐)

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Ponatinib CAS号 943319-70-8

基本信息

CAS(化学文摘登记)号

943319-70-8

英文名称

Ponatinib

英文化学名

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

简化分子线性输入规范(SMILES)

CC1=CC=C(C(NC2=CC(C(F)(F)F)=C(CN3CCN(C)CC3)C=C2)=O)C=C1C#CC4=CN=C5N4N=CC=C5

分子式

C29H27F3N6O

分子量

532.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Ponatinib is chemically 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide. Ponatinib is supplied with detailed characterization data compliant with regulatory guideline. Ponatinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ponatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ponatinib-cas-943319-70-8/

相关产品

1114544-31-8 (盐酸盐)

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