文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Paclitaxel 杂质 13

英文化学名

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-4-(((2,2-dichloroethoxy)carbonyl)oxy)-9,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

简化分子线性输入规范(SMILES)

CC1(C)C2=C(C)[C@@H](O)C[C@@]1(O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]5OC(OCC(Cl)Cl)=O)([H])[C@]5(C)C([C@@H]2OC(C)=O)=O

分子式

C34H40Cl2O13

分子量

727.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 13 is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-4-(((2,2-dichloroethoxy)carbonyl)oxy)-9,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. Paclitaxel Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-13-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Paclitaxel 杂质 11

英文化学名

(3R,4R)-1-benzoyl-4-phenyl-3-((triethylsilyl)oxy)azetidin-2-one

简化分子线性输入规范(SMILES)

O=C1N(C(C2=CC=CC=C2)=O)[C@H](C3=CC=CC=C3)[C@H]1O[Si](CC)(CC)CC

分子式

C22H27NO3Si

分子量

381.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 11 is chemically (3R,4R)-1-benzoyl-4-phenyl-3-((triethylsilyl)oxy)azetidin-2-one. Paclitaxel Impurity 11 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 11 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-11-cas-N/A/

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基本信息

CAS(化学文摘登记)号

1432793-93-5

英文名称

Paclitaxel 杂质 10

英文化学名

(3S,4S)-3-hydroxy-4-phenylazetidin-2-one

简化分子线性输入规范(SMILES)

O=C1N[C@@H](C2=CC=CC=C2)[C@@H]1O

分子式

C9H9NO2

分子量

163.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 10 is chemically (3S,4S)-3-hydroxy-4-phenylazetidin-2-one. Paclitaxel Impurity 10 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-10-cas-1432793-93-5/

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基本信息

CAS(化学文摘登记)号

1432794-04-1

英文名称

Paclitaxel 杂质 9

英文化学名

(3R,4R)-3-hydroxy-4-phenylazetidin-2-one

简化分子线性输入规范(SMILES)

O=C1N[C@H](C2=CC=CC=C2)[C@H]1O

分子式

C9H9NO2

分子量

163.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 9 is chemically (3R,4R)-3-hydroxy-4-phenylazetidin-2-one. Paclitaxel Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-9-cas-1432794-04-1/

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基本信息

CAS(化学文摘登记)号

162459-94-1

英文名称

Paclitaxel 杂质 8

英文化学名

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoyl)oxy)-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-((triethylsilyl)oxy)-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

简化分子线性输入规范(SMILES)

CC(O[C@@]1([C@](C[C@@H]2O[Si](CC)(CC)CC)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@]4(C[C@H](OC([C@H](O[Si](C)(C)C(C)(C)C)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C(C)=C(C4(C)C)[C@H]3OC(C)=O)O)O)=O

分子式

C52H75NO13Si2

分子量

978.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 8 is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoyl)oxy)-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-((triethylsilyl)oxy)-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. Paclitaxel Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-8-cas-162459-94-1/

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基本信息

CAS(化学文摘登记)号

158948-96-0

英文名称

Paclitaxel EP 杂质 R

英文化学名

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,11-dihydroxy-9-(((2R,3S)-2-hydroxy-3-((S)-2-methylbutanamido)-3-phenylpropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

简化分子线性输入规范(SMILES)

CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC([C@@H](C)CC)=O)=O)C(C)=C4[C@H]3OC(C)=O)O)OC(C6=CC=CC=C6)=O)=O

分子式

C45H55NO14

分子量

833.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel EP Impurity R is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,11-dihydroxy-9-(((2R,3S)-2-hydroxy-3-((S)-2-methylbutanamido)-3-phenylpropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. It is also known as Taxol E ; Paclitaxel Sec-Butyl analog. Paclitaxel EP Impurity R is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel EP Impurity R can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxelep-impurity-r-cas-158948-96-0/

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基本信息

CAS(化学文摘登记)号

1262147-55-6

英文名称

Paclitaxel 杂质 49

英文化学名

5-​Oxazolidinecarboxyli​c acid, 3-​benzoyl-​2-​(4-​methoxyphenyl)​-​4-​phenyl-​, (4R,​5R)​-; (4R,5R)-3-benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid;

简化分子线性输入规范(SMILES)

COC1=CC=C(C2O[C@@H](C(O)=O)[C@@H](C3=CC=CC=C3)N2C(C4=CC=CC=C4)=O)C=C1

分子式

C24H21NO5

分子量

403.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 49 is chemically 5-​Oxazolidinecarboxyli​c acid, 3-​benzoyl-​2-​(4-​methoxyphenyl)​-​4-​phenyl-​, (4R,​5R)​-; (4R,5R)-3-benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid;. It is also known as (4R,5R)-3-Benzoyl-2-(4-anisyl)-4-Phenyl-5-Oxazolidinecarboxylic Acid. Paclitaxel Impurity 49 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 49 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/4r5r-3-benzoyl-2-4-anisyl-4-phenyl-5-oxazolidinecarboxylic-acid-cas-1262147-55-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Paclitaxel 杂质 5

英文化学名

(4S,4aS,6R,9S,11S,12S,12bS)-12-(benzoyloxy)-9-(((2R,3S)-3-((E)-hex-3-enamido)-2-(((E)-hex-3-enoyl)oxy)-3-phenylpropanoyl)oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

简化分子线性输入规范(SMILES)

CC1=C([C@@H](OC(C)=O)C([C@@]2(C)C([C@@](CO3)(OC(C)=O)C3C[C@@H]2O)[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C[C@@H]1OC([C@H](OC(C/C=C/CC)=O)[C@@H](NC(C/C=C/CC)=O)C6=CC=CC=C6)=O

分子式

C52H63NO15

分子量

942.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 5 is chemically (4S,4aS,6R,9S,11S,12S,12bS)-12-(benzoyloxy)-9-(((2R,3S)-3-((E)-hex-3-enamido)-2-(((E)-hex-3-enoyl)oxy)-3-phenylpropanoyl)oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. Paclitaxel Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-5-cas-N/A/

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基本信息

CAS(化学文摘登记)号

159001-24-8

英文名称

Paclitaxel 杂质 4

英文化学名

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,11-dihydroxy-9-(((2R,3S)-2-hydroxy-3-((R)-2-methylbutanamido)-3-phenylpropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

简化分子线性输入规范(SMILES)

CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC([C@H](C)CC)=O)=O)C(C)=C4[C@H]3OC(C)=O)O)OC(C6=CC=CC=C6)=O)=O

分子式

C45H55NO14

分子量

833.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Paclitaxel Impurity 4 is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,11-dihydroxy-9-(((2R,3S)-2-hydroxy-3-((R)-2-methylbutanamido)-3-phenylpropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. Paclitaxel Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/paclitaxel-impurity-4-cas-159001-24-8/

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基本信息

CAS(化学文摘登记)号

171926-87-7

英文名称

2-Debenzoyl-2-Tigloyl 10-Deacetyl Baccatin III

英文化学名

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl (E)-2-methylbut-2-enoate

简化分子线性输入规范(SMILES)

C/C=C(C)/C(O[C@@H]1[C@]2(O)C[C@H](O)C(C)=C(C2(C)C)[C@@H](O)C([C@@]3(C)[C@@]1([H])[C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)=O)=O

分子式

C27H38O10

分子量

522.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

2-Debenzoyl-2-Tigloyl 10-Deacetyl Baccatin III is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl (E)-2-methylbut-2-enoate. 2-Debenzoyl-2-Tigloyl 10-Deacetyl Baccatin III is supplied with detailed characterization data compliant with regulatory guideline. 2-Debenzoyl-2-Tigloyl 10-Deacetyl Baccatin III can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/2-debenzoyl-2-tigloyl-10-deacetyl-baccatin-iii-cas-171926-87-7/

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