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Nebivolol 杂质 58 CAS号 99199-60-7

基本信息

CAS(化学文摘登记)号

99199-60-7

英文名称

Nebivolol 杂质 58

英文化学名

6-Fluorochromane-2-carboxylic acid

简化分子线性输入规范(SMILES)

O=C(C1CCC2=C(O1)C=CC(F)=C2)O

分子式

C10H9FO3

分子量

196.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Impurity 58 is chemically 6-Fluorochromane-2-carboxylic acid. Nebivolol Impurity 58 is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Impurity 58 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-impurity-58-cas-99199-60-7/

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Nebivolol 杂质 56 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol 杂质 56

英文化学名

(2R,6S)-4-benzyl-2-((S)-6-fluorochroman-2-yl)-6-(6-fluorochroman-2-yl)morpholin-2-ol compound with (2S,6S)-4-benzyl-2-((R)-6-fluorochroman-2-yl)-6-(6-fluorochroman-2-yl)morpholin-2-ol (1:1)

简化分子线性输入规范(SMILES)

FC1=CC=C(O2)C(CC[C@@H]2[C@]3(O)CN(CC4=CC=CC=C4)C[C@@H](C5CCC6=CC(F)=CC=C6O5)O3)=C1.FC7=CC=C(O8)C(CC[C@H]8[C@@]9(O)CN(CC%10=CC=CC=C%10)C[C@@H](C%11CCC%12=CC(F)=CC=C%12O%11)O9)=C7

分子式

C29H29F2NO4

分子量

493.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Impurity 56 is chemically (2R,6S)-4-benzyl-2-((S)-6-fluorochroman-2-yl)-6-(6-fluorochroman-2-yl)morpholin-2-ol compound with (2S,6S)-4-benzyl-2-((R)-6-fluorochroman-2-yl)-6-(6-fluorochroman-2-yl)morpholin-2-ol (1:1). Nebivolol Impurity 56 is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Impurity 56 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-impurity-56-cas-N/A/

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Nebivolol Ethyl Carbonyl Carbonate CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol Ethyl Carbonyl Carbonate

英文化学名

(R)-(ethyl carbonic) (R)-6-fluorochromane-2-carboxylic anhydride compound with (S)-(ethyl carbonic) (S)-6-fluorochromane-2-carboxylic anhydride (1:1)

简化分子线性输入规范(SMILES)

FC1=CC(CC[C@H](C(OC(OCC)=O)=O)O2)=C2C=C1.FC3=CC(CC[C@@H](C(OC(OCC)=O)=O)O4)=C4C=C3

分子式

C13H13FO5

分子量

268.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Ethyl Carbonyl Carbonate is chemically (R)-(ethyl carbonic) (R)-6-fluorochromane-2-carboxylic anhydride compound with (S)-(ethyl carbonic) (S)-6-fluorochromane-2-carboxylic anhydride (1:1). Nebivolol Ethyl Carbonyl Carbonate is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Ethyl Carbonyl Carbonate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-ethyl-carbonyl-carbonate-cas-N/A/

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Nebivolol Threo Desfluoro 杂质 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol Threo Desfluoro 杂质

英文化学名

(R)-2-((R)-Oxiran-2-yl)chromane compound with (S)-2-((S)-oxiran-2-yl)chromane (1:1)

简化分子线性输入规范(SMILES)

[H][C@]1(CO1)[C@@]2([H])OC3=CC=CC=C3CC2.[H][C@@]4(CO4)[C@]5([H])OC6=CC=CC=C6CC5

分子式

C11H12O2

分子量

176.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Threo Desfluoro Impurity is chemically (R)-2-((R)-Oxiran-2-yl)chromane compound with (S)-2-((S)-oxiran-2-yl)chromane (1:1). It is also known as Mixture of 1029684-25-0 and 99199-87-8. Nebivolol Threo Desfluoro Impurity is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Threo Desfluoro Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-threo-desfluoro-impurity-cas-N/A/

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Nebivolol 杂质 54 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol 杂质 54

英文化学名

[(1RS)-1-[(2RS)-3,4-Dihydro-2H-1-benzopyran-2-yl]-2-[[(2RS-2-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethane-1-ol]

简化分子线性输入规范(SMILES)

FC(C=C1)=CC2=C1O[C@@](CC2)([H])[C@]([H])(O)CNC[C@@]([H])(O)[C@@](O3)([H])CCC4=C3C=CC(F)=C4

分子式

C22H25F2NO4

分子量

405.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Impurity 54 is chemically [(1RS)-1-[(2RS)-3,4-Dihydro-2H-1-benzopyran-2-yl]-2-[[(2RS-2-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethane-1-ol]. Nebivolol Impurity 54 is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Impurity 54 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-impurity-54-cas-N/A/

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Nebivolol 杂质 53 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol 杂质 53

英文化学名

(R)-2-((S)-6-fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate compound with (S)-2-((R)-6-fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate (1:1)

简化分子线性输入规范(SMILES)

CC(OC[C@@H]([C@H]1CCC2=CC(F)=CC=C2O1)OS(=O)(C3=CC=C(C)C=C3)=O)=O.CC(OC[C@H]([C@@H]4CCC5=CC(F)=CC=C5O4)OS(=O)(C6=CC=C(C)C=C6)=O)=O

分子式

C20H21FO6S

分子量

408.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Impurity 53 is chemically (R)-2-((S)-6-fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate compound with (S)-2-((R)-6-fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate (1:1). Nebivolol Impurity 53 is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Impurity 53 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-impurity-53-cas-N/A/

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Nebivolol EP 杂质 A CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol EP 杂质 A

英文化学名

(1RS)-1-[(2RS)-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2RS)-2-[(2SR)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethan-1-ol (as per EP)

简化分子线性输入规范(SMILES)

O[C@@H]([C@@]1([H])CCC2=C(O1)C=CC=C2)CNC[C@H]([C@]3([H])CCC4=C(O3)C=CC(F)=C4)O

分子式

C22H26FNO4

分子量

387.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol EP Impurity A is chemically (1RS)-1-[(2RS)-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2RS)-2-[(2SR)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethan-1-ol (as per EP). Nebivolol EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-ep-impurity-a-cas-N/A/

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Nebivolol 杂质 52 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Nebivolol 杂质 52

英文化学名

2,2′-(Benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethan-1-ol) oxalate

简化分子线性输入规范(SMILES)

OC(C1CCC2=C(O1)C=CC(F)=C2)CN(CC(C3CCC4=C(O3)C=CC(F)=C4)O)CC5=CC=CC=C5.O=C(O)C(O)=O

分子式

C29H31F2NO4 : C2H2O4

分子量

495.6 : 90.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Impurity 52 is chemically 2,2′-(Benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethan-1-ol) oxalate. Nebivolol Impurity 52 is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Impurity 52 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-impurity-52-cas-N/A/

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N-Nitroso Nebivolol D4 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Nebivolol D4

英文化学名

N-((S)-2-((R)-6-Fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)-N-((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)nitrous amide

简化分子线性输入规范(SMILES)

FC1=CC(CC[C@]([C@@H](O)C([2H])([2H])N(N=O)C([2H])([2H])[C@H](O)[C@@]2([H])CCC(C=C(F)C=C3)=C3O2)([H])O4)=C4C=C1

分子式

C22H20D4F2N2O5

分子量

438.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Nebivolol D4 is chemically N-((S)-2-((R)-6-Fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)-N-((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)nitrous amide. N-Nitroso Nebivolol D4 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Nebivolol D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-nebivolol-d4-cas-N/A/

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Nebivolol 相关化合物 D CAS号 197706-51-7

基本信息

CAS(化学文摘登记)号

197706-51-7

英文名称

Nebivolol 相关化合物 D

英文化学名

(S)-6-Fluoro-2-((R)-oxiran-2-yl)chromane

简化分子线性输入规范(SMILES)

[H][C@]1([C@H](CNC[C@@H](O)[C@]2(CCC3=CC(F)=CC=C3O2)[H])O)CCC4=CC(F)=CC=C4O1

分子式

C11H11FO2

分子量

194.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Nebivolol Related Compound D is chemically (S)-6-Fluoro-2-((R)-oxiran-2-yl)chromane. Nebivolol Related Compound D is supplied with detailed characterization data compliant with regulatory guideline. Nebivolol Related Compound D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/nebivolol-related-compound-d-cas-197706-51-7/

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