文章

基本信息

CAS(化学文摘登记)号

79902-20-8

英文名称

Lovastatin 杂质 3

英文化学名

(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl (S)-2-methylbutanoate

简化分子线性输入规范(SMILES)

C[C@]([H])(C(O[C@]1(C[C@@](C)(C=C2CC[C@@]([H])([C@@]([H])([C@]21[H])CC[C@](C[C@]([H])(CC3=O)O)(O3)[H])C)[H])[H])=O)CC

分子式

C24H38O5

分子量

406.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Impurity 3 is chemically (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl (S)-2-methylbutanoate. Lovastatin Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-impurity-3-cas-79902-20-8/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Lovastatin Keto 杂质

英文化学名

(8aR)-8-(2-((2R,4S)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methyl-3-oxobutanoate

简化分子线性输入规范(SMILES)

O=C(C(C)C(C)=O)OC1[C@@]2([H])C(C=CC(C)C2CC[C@H]3OC(C[C@@H](O)C3)=O)=CC(C)C1

分子式

C24H34O6

分子量

418.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Keto Impurity is chemically (8aR)-8-(2-((2R,4S)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methyl-3-oxobutanoate. Lovastatin Keto Impurity is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Keto Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-keto-impurity-cas-N/A/

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基本信息

CAS(化学文摘登记)号

77934-80-6

英文名称

Lovastatin 杂质 1

英文化学名

Methyl (3R,5R)-7-((1S,2S,6R,8S,8aR)-2,6-dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate

简化分子线性输入规范(SMILES)

O[C@@H](C[C@@H](O)CC(OC)=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@H](C)C2)([H])[C@H]2OC([C@@H](C)CC)=O

分子式

C25H40O6

分子量

436.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Impurity 1 is chemically Methyl (3R,5R)-7-((1S,2S,6R,8S,8aR)-2,6-dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate. Lovastatin Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-impurity-1-cas-77934-80-6/

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基本信息

CAS(化学文摘登记)号

1649450-58-7

英文名称

Cis-2,3-Dehydro Lovastatin Acid Sodium Salt

英文化学名

Sodium (2Z,​5R)​-7-​[(1S,​2S,​6R,​8S,​8aR)​-​1,​2,​6,​7,​8,​8a-​Hexahydro-​2,​6-​dimethyl-​8-​[(2S)​-​2-​methyl-​1-​oxobutoxy]​-​1-​naphthalenyl]​-​5-​hydroxy-​2-​heptenoic Acid

简化分子线性输入规范(SMILES)

O[C@@H](C/C=CC([O-])=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@H](C)C2)([H])[C@H]2OC([C@@H](C)CC)=O.[Na+]

分子式

C24H35O5 : Na

分子量

403.5 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Cis-2,3-Dehydro Lovastatin Acid Sodium Salt is chemically Sodium (2Z,​5R)​-7-​[(1S,​2S,​6R,​8S,​8aR)​-​1,​2,​6,​7,​8,​8a-​Hexahydro-​2,​6-​dimethyl-​8-​[(2S)​-​2-​methyl-​1-​oxobutoxy]​-​1-​naphthalenyl]​-​5-​hydroxy-​2-​heptenoic Acid. Cis-2,3-Dehydro Lovastatin Acid Sodium Salt is supplied with detailed characterization data compliant with regulatory guideline. Cis-2,3-Dehydro Lovastatin Acid Sodium Salt can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cis-23-dehydro-lovastatin-acid-sodium-salt-cas-1649450-58-7/

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1649503-10-5 (游离碱)

基本信息

CAS(化学文摘登记)号

79952-44-6

英文名称

Epi Lovastatin

英文化学名

(2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester

简化分子线性输入规范(SMILES)

O=C([C@H](C)CC)O[C@@H]1[C@@]([C@H]2CC[C@@H](OC3=O)C[C@H](C3)O)([H])C(C=C[C@@H]2C)=C[C@H](C)C1

分子式

C24H36O5

分子量

404.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Epi Lovastatin is chemically (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Epi Lovastatin is supplied with detailed characterization data compliant with regulatory guideline. Epi Lovastatin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/epi-lovastatin-cas-79952-44-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Lovastatin 杂质 2

英文化学名

(1S,3R,7S,8S,8aR)-8-(2-((S)-4,6-dioxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (R)-2-methylbutanoate

简化分子线性输入规范(SMILES)

[H][C@@]12C(C=C[C@H](C)[C@]2([H])CC[C@@]3([H])CC(CC(O3)=O)=O)=C[C@H](C)C[C@@H]1OC([C@H](C)CC)=O

分子式

C24H34O5

分子量

402.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Impurity 2 is chemically (1S,3R,7S,8S,8aR)-8-(2-((S)-4,6-dioxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (R)-2-methylbutanoate. Lovastatin Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-impurity-2-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Lovastatin Hydroxy Acid 3,5-Acetonide

英文化学名

2-((4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-2,6-dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid

简化分子线性输入规范(SMILES)

O=C([C@@H](C)CC)O[C@@H]1[C@@]2([H])C(C=C[C@H](C)[C@@H]2CC[C@H]3OC(C)(C)O[C@@H](CC(O)=O)C3)=C[C@H](C)C1

分子式

C27H42O6

分子量

462.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Hydroxy Acid 3,5-Acetonide is chemically 2-((4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-2,6-dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid. Lovastatin Hydroxy Acid 3,5-Acetonide is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Hydroxy Acid 3,5-Acetonide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-hydroxy-acid-35-acetonide-cas-N/A/

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基本信息

CAS(化学文摘登记)号

79902-31-1

英文名称

Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether

英文化学名

(4R,6R)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-2H-pyran-2-one

简化分子线性输入规范(SMILES)

C[C@@H](C=C1)[C@@H]([C@]2([H])C1=C[C@H](C)C[C@@H]2O)CC[C@@H](OC3=O)C[C@H](C3)O[Si](C)(C)C(C)(C)C

分子式

C25H42O4Si

分子量

434.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether is chemically (4R,6R)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-2H-pyran-2-one. Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-diol-lactone-4-tert-butyldimethylsilyl-ether-cas-79902-31-1/

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基本信息

CAS(化学文摘登记)号

1002345-93-8

英文名称

Lovastatin-D3

英文化学名

(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-(methyl-d3)butanoate

简化分子线性输入规范(SMILES)

O=C([C@@H](C([2H])([2H])[2H])CC)O[C@@H]1[C@@]([C@H]2CC[C@@H](OC3=O)C[C@H](C3)O)([H])C(C=C[C@@H]2C)=C[C@H](C)C1

分子式

C24H33D3O5

分子量

407.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin-D3 is chemically (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-(methyl-d3)butanoate. Lovastatin-D3 is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin-D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-d3-cas-1002345-93-8/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Lovastatin Hydroxy 杂质

英文化学名

(3R,7S,8aR)-8-(2-((2R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 3-hydroxy-2-methylbutanoate

简化分子线性输入规范(SMILES)

O=C(C(C)C(O)C)OC1[C@@]2([H])C(C=C[C@H](C)C2CC[C@H]3OC(CC(O)C3)=O)=C[C@H](C)C1

分子式

C24H36O6

分子量

420.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lovastatin Hydroxy Impurity is chemically (3R,7S,8aR)-8-(2-((2R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 3-hydroxy-2-methylbutanoate. Lovastatin Hydroxy Impurity is supplied with detailed characterization data compliant with regulatory guideline. Lovastatin Hydroxy Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lovastatin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lovastatin-hydroxy-impurity-cas-N/A/

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