文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Lorlatinib 杂质 2

英文化学名

N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)amino)methyl)-N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)nitrous amide

简化分子线性输入规范(SMILES)

FC1=CC=C(C(N(C)CC2=NN(C)C(C#N)=C2C3=CC4=C(N(N=O)CNC5=NC(C6=C(C#N)N(C)N=C6CN7C)=CC(O[C@H](C)C8=CC(F)=CC=C8C7=O)=C5)N=C3)=O)C([C@@H](C)O4)=C1

分子式

C43H37F2N13O5

分子量

853.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Lorlatinib Impurity 2 is chemically N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)amino)methyl)-N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)nitrous amide. N-Nitroso Lorlatinib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-lorlatinib-impurity-2-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Lorlatinib 杂质-4

英文化学名

(R)-2-(1-((2-Amino-5-(5-cyano-1-methyl-3-((methyl(nitroso)amino)methyl)-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acid

简化分子线性输入规范(SMILES)

FC1=CC([C@@H](C)OC2=C(N)N=CC(C3=C(C#N)N(C)N=C3CN(N=O)C)=C2)=C(C(O)=O)C=C1

分子式

C21H20FN7O4

分子量

453.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Lorlatinib impurity-4 is chemically (R)-2-(1-((2-Amino-5-(5-cyano-1-methyl-3-((methyl(nitroso)amino)methyl)-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acid. N-Nitroso Lorlatinib impurity-4 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib impurity-4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-lorlatinib-impurity-4-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Lorlatinib 杂质 1

英文化学名

N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)-N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)(nitroso)amino)methyl)nitrous amide

简化分子线性输入规范(SMILES)

FC1=CC=C(C(N(C)CC2=NN(C)C(C#N)=C2C3=CC4=C(N(N=O)CN(C5=NC(C6=C(C#N)N(C)N=C6CN7C)=CC(O[C@H](C)C8=CC(F)=CC=C8C7=O)=C5)N=O)N=C3)=O)C([C@@H](C)O4)=C1

分子式

C43H36F2N14O6

分子量

882.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Lorlatinib Impurity 1 is chemically N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)-N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)(nitroso)amino)methyl)nitrous amide. N-Nitroso Lorlatinib Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-lorlatinib-impurity-1-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

1454846-35-5

英文名称

Lorlatinib

英文化学名

(R)-26-amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile

简化分子线性输入规范(SMILES)

N#CC(N1C)=C(C(CN(C(C2=CC=C(F)C=C32)=O)C)=N1)C4=CN=C(N)C(O[C@@H]3C)=C4

分子式

C21H19FN6O2

分子量

406.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lorlatinib is chemically (R)-26-amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile. Lorlatinib is supplied with detailed characterization data compliant with regulatory guideline. Lorlatinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lorlatinib-cas-1454846-35-5/

相关产品

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Lorlatinib 13CD3

英文化学名

(R)-26-amino-55-fluoro-11,4-dimethyl-7-(methyl-13C-d3)-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile

简化分子线性输入规范(SMILES)

N#CC(N1C)=C(C(CN(C(C2=CC=C(F)C=C32)=O)[13C]([2H])([2H])[2H])=N1)C4=CN=C(N)C(O[C@@H]3C)=C4

分子式

C2013CH16D3FN6O2

分子量

410.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Lorlatinib 13CD3 is chemically (R)-26-amino-55-fluoro-11,4-dimethyl-7-(methyl-13C-d3)-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile. Lorlatinib 13CD3 is supplied with detailed characterization data compliant with regulatory guideline. Lorlatinib 13CD3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/lorlatinib-13cd3-cas-N/A/

相关产品

1454846-35-5 (Unlabelled)