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N-Acetyl Linaclotide 杂质 CAS号 1422389-17-0

基本信息

CAS(化学文摘登记)号

1422389-17-0

英文名称

N-Acetyl Linaclotide 杂质

英文化学名

((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-48,50-dimercapto-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-propanopyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine

简化分子线性输入规范(SMILES)

OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@@H](NC(CNC([C@H]([C@H](O)C)NC([C@@](C(CC2S)S)([H])NC([C@H](C)NC([C@@](CCC3)([H])N3C([C@H](CC(N)=O)NC([C@]4([H])CSSC[C@H](NC(C)=O)C(N[C@]2([H])C(N[C@@H](CCC(O)=O)C(N[C@H]5CC6=CC=C(O)C=C6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@](C(N4)=O)([H])NC5=O)=O

分子式

C62H83N15O22S6

分子量

1582.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Acetyl Linaclotide Impurity is chemically ((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-48,50-dimercapto-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-propanopyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine. N-Acetyl Linaclotide Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Acetyl Linaclotide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-acetyl-linaclotide-impurity-cas-1422389-17-0/

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Acetylated Linaclotide CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Acetylated Linaclotide

英文化学名

3-(25-Acetamido-6-((1-carboxy-2-(4-hydroxyphenyl)ethyl)carbamoyl)-38-(2-carboxyethyl)-35-(4-hydroxybenzyl)-12-(1-hydroxyethyl)-8,11,14,22,24,32,34,37,40-nonaoxo-15-(2-propionamidopropanamido)-3,4,17,18,27,28-hexathia-7,10,13,23,31,33,36,39-octaazabicyclo[18.12.8]tetracontane-30-carboxamido)-4-cyclopentyl-4-oxobutanoic acid

简化分子线性输入规范(SMILES)

OC1=CC=C(CC(NC(C(NC(CNC(C(C(O)C)NC(C(CSSCC(CC(N2)=O)C3=O)NC(C(NC(CC)=O)C)=O)=O)=O)=O)CSSCC(NC(C(NC(C(N3)CCC(O)=O)=O)CC4=CC=C(O)C=C4)=O)C(NC(CSSCC(NC(C)=O)C2=O)C(NC(CC(O)=O)C(C5CCCC5)=O)=O)=O)=O)C(O)=O)C=C1

分子式

C66H89N13O24S6

分子量

1640.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Acetylated Linaclotide is chemically 3-(25-Acetamido-6-((1-carboxy-2-(4-hydroxyphenyl)ethyl)carbamoyl)-38-(2-carboxyethyl)-35-(4-hydroxybenzyl)-12-(1-hydroxyethyl)-8,11,14,22,24,32,34,37,40-nonaoxo-15-(2-propionamidopropanamido)-3,4,17,18,27,28-hexathia-7,10,13,23,31,33,36,39-octaazabicyclo[18.12.8]tetracontane-30-carboxamido)-4-cyclopentyl-4-oxobutanoic acid. Acetylated Linaclotide is supplied with detailed characterization data compliant with regulatory guideline. Acetylated Linaclotide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/acetylated-linaclotide-cas-N/A/

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Linaclotide CAS号 851199-59-2

基本信息

CAS(化学文摘登记)号

851199-59-2

英文名称

Linaclotide

英文化学名

L-Cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-tyrosine Cyclic (1→6),(2→10),(5→13)-Tris(disulfide)

简化分子线性输入规范(SMILES)

OC1=CC=C(C[C@H](NC([C@@H](NC([C@H](CSSC2)NC([C@H](CSSC3)N)=O)=O)CCC(O)=O)=O)C(N[C@@H](CSSC4)C(N[C@@H]3C(N[C@H](C(N5CCC[C@@]5([H])C(N[C@@H](C)C(N[C@@H]2C(N[C@]([C@@H](C)O)([H])C(NCC(N[C@@H]4C(N[C@@H](CC6=CC=C(O)C=C6)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CC(N)=O)=O)=O)=O)C=C1

分子式

C59H79N15O21S6

分子量

1526.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Linaclotide is chemically L-Cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-tyrosine Cyclic (1→6),(2→10),(5→13)-Tris(disulfide). Linaclotide is supplied with detailed characterization data compliant with regulatory guideline. Linaclotide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/linaclotide-cas-851199-59-2/

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Linaclotide Des-Tyrosine 杂质 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Linaclotide Des-Tyrosine 杂质

英文化学名

(3S,6R,9R,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-(1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-1H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28,5,8,11,14,17,20,23,32,35,38,41]tetrathiaundecaazacyclotritetracontine-15-carboxylic acid

简化分子线性输入规范(SMILES)

O=C([C@@H](NC(CNC([C@@H](C(O)C)NC([C@@](C(CC1S)S)([H])NC([C@H](C)NC([C@@](CCC2)([H])N2C([C@H](CC(N)=O)NC([C@]3([H])CSSC[C@H](N)C(N[C@]1([H])C(N[C@@H](CCC(O)=O)C(N[C@H]4CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@](C(N3)=O)([H])NC4=O)O

分子式

C51H72N14O19S6

分子量

1377.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Linaclotide Des-Tyrosine Impurity is chemically (3S,6R,9R,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-(1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-1H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28,5,8,11,14,17,20,23,32,35,38,41]tetrathiaundecaazacyclotritetracontine-15-carboxylic acid. Linaclotide Des-Tyrosine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Linaclotide Des-Tyrosine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/linaclotide-des-tyrosine-impurity-cas-N/A/

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Aspartic Acid Linaclotide 杂质 CAS号 1207977-38-5

基本信息

CAS(化学文摘登记)号

1207977-38-5

英文名称

Aspartic Acid Linaclotide 杂质

英文化学名

((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Amino-26-(2-carboxyethyl)-40-(carboxymethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine

简化分子线性输入规范(SMILES)

O=C1N2[C@@](C(N[C@H](C(N[C@]3([H])C(N[C@@](C(NCC(N[C@@H](CSSC[C@@]4([H])C(N[C@](CSSC[C@@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N4)=O)CC5=CC=C(C=C5)O)=O)CCC(O)=O)=O)([H])CSSC3)=O)N)([H])C(N[C@H]1CC(O)=O)=O)=O)C(N[C@H](C(O)=O)CC6=CC=C(C=C6)O)=O)=O)=O)([H])[C@H](O)C)=O)=O)C)=O)([H])CCC2

分子式

C59H78N14O22S6

分子量

1527.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Aspartic Acid Linaclotide Impurity is chemically ((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Amino-26-(2-carboxyethyl)-40-(carboxymethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine. Aspartic Acid Linaclotide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Aspartic Acid Linaclotide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/aspartic-acid-linaclotide-impurity-cas-1207977-38-5/

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