文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ivacaftor Nitroso 杂质 5

英文化学名

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

简化分子线性输入规范(SMILES)

O=C(OCC)/C(C(OCC)=O)=C/N(N=O)C1=CC=CC=C1

分子式

C14H16N2O5

分子量

292.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Nitroso Impurity 5 is chemically Diethyl 2-((nitroso(phenyl)amino)methylene)malonate. Ivacaftor Nitroso Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Nitroso Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-nitroso-impurity-5-cas-N/A/

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基本信息

CAS(化学文摘登记)号

52980-28-6

英文名称

Ivacaftor 杂质 12

英文化学名

Ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

简化分子线性输入规范(SMILES)

O=C(C1=CNC2=C(C=CC=C2)C1=O)OCC

分子式

C12H11NO3

分子量

217.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Impurity 12 is chemically Ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate. Ivacaftor Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-impurity-12-cas-52980-28-6/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ivacaftor Nitroso 杂质 6

英文化学名

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

简化分子线性输入规范(SMILES)

O=NN(C=C1C(OCC)=O)C2=CC=CC=C2C1=O

分子式

C12H10N2O4

分子量

246.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Nitroso Impurity 6 is chemically Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate. Ivacaftor Nitroso Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Nitroso Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-nitroso-impurity-6-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ivacaftor 杂质 17

英文化学名

N-(3-(Tert-butyl)-4-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CNC2=C(C=CC=C2)C1=O)NC3=CC=C(O)C(C(C)(C)C)=C3

分子式

C20H20N2O3

分子量

336.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Impurity 17 is chemically N-(3-(Tert-butyl)-4-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Ivacaftor Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-impurity-17-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Ivacaftor Ortho Isomer

英文化学名

N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CN(N=O)C2=C(C=CC=C2)C1=O)NC3=CC(C(C)(C)C)=CC(C(C)(C)C)=C3O

分子式

C24H27N3O4

分子量

421.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Ivacaftor Ortho Isomer is chemically N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide. N-Nitroso Ivacaftor Ortho Isomer is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Ivacaftor Ortho Isomer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-ivacaftor-ortho-isomer-cas-N/A/

相关产品

基本信息

CAS(化学文摘登记)号

2760759-55-3

英文名称

Ivacaftor 杂质 18

英文化学名

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

简化分子线性输入规范(SMILES)

O=C(C1=CNC2=C(C=CC=C2)C1=O)OC3=CC(NC(C4=CNC5=C(C=CC=C5)C4=O)=O)=C(C(C)(C)C)C=C3C(C)(C)C

分子式

C34H33N3O5

分子量

563.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Impurity 18 is chemically 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate. Ivacaftor Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-impurity-18-cas-2760759-55-3/

相关产品

基本信息

CAS(化学文摘登记)号

1246213-41-1

英文名称

Ivacaftor Carboxylic Acid Lactone

英文化学名

N-(5-(Tert-butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

简化分子线性输入规范(SMILES)

CC1(C(C(OC1=O)=C2)=CC(C(C)(C)C)=C2NC(C3=CNC4=CC=CC=C4C3=O)=O)C

分子式

C24H24N2O4

分子量

404.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Carboxylic Acid Lactone is chemically N-(5-(Tert-butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Ivacaftor Carboxylic Acid Lactone is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Carboxylic Acid Lactone can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-carboxylic-acid-lactone-cas-1246213-41-1/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Ivacaftor 杂质 16

英文化学名

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic acid

简化分子线性输入规范(SMILES)

O=C1C(C(NC2=CC(O)=C(C(C)(C)C)C=C2C(C)(C)C)=O)=CN(C(CCC(O)=O)=O)C3=CC=CC=C31

分子式

C28H32N2O6

分子量

492.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Impurity 16 is chemically 4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic acid. Ivacaftor Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-impurity-16-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Metabolite M1 (hydroxymethyl-Ivacaftor)

英文化学名

N-(2-(Tert-butyl)-5-hydroxy-4-(2-hydroxypropan-2-yl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=CNC2=C(C=CC=C2)C1=O)NC3=CC(O)=C(C(C)(O)C)C=C3C(C)(C)C

分子式

C23H26N2O4

分子量

394.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Metabolite M1 (hydroxymethyl-Ivacaftor)  is chemically N-(2-(Tert-butyl)-5-hydroxy-4-(2-hydroxypropan-2-yl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Metabolite M1 (hydroxymethyl-Ivacaftor)  is supplied with detailed characterization data compliant with regulatory guideline. Metabolite M1 (hydroxymethyl-Ivacaftor)  can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/pidotimod-impurity-1-cas-N/A/

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基本信息

CAS(化学文摘登记)号

1233530-92-1

英文名称

Ivacaftor 杂质 15

英文化学名

2-Bromo-4-(tert-butyl)-5-nitrophenyl methyl carbonate

简化分子线性输入规范(SMILES)

O=[N](C(C=C1OC(OC)=O)=C(C=C1Br)C(C)(C)C)=O

分子式

C12H14BrNO5

分子量

332.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Ivacaftor Impurity 15 is chemically 2-Bromo-4-(tert-butyl)-5-nitrophenyl methyl carbonate. Ivacaftor Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Ivacaftor Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivacaftor. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/ivacaftor-impurity-15-cas-1233530-92-1/

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