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Irinotecan 杂质 4 CAS号 121080-63-5

基本信息

CAS(化学文摘登记)号

121080-63-5

英文名称

Irinotecan 杂质 4

英文化学名

6-(((S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

简化分子线性输入规范(SMILES)

OC1C(OC2=CC=C(N=C(C(N3C4)=CC([C@@](O)(CC)C(OC5)=O)=C5C3=O)C4=C6CC)C6=C2)OC(C(O)=O)C(O)C1O

分子式

C28H28N2O11

分子量

568.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan Impurity 4 is chemically 6-(((S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Irinotecan Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-impurity-4-cas-121080-63-5/

相关产品

121080-64-6 (钠盐)

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Irinotecan 杂质 2 CAS号 143490-54-4

基本信息

CAS(化学文摘登记)号

143490-54-4

英文名称

Irinotecan 杂质 2

英文化学名

3,10-Diethyl-3-hydroxy-13-oxo-11,13-dihydro-1H,3H-furo[3′,4′:6,7]indolizino[1,2-b]quinolin-8-yl [1,4′-bipiperidine]-1′-carboxylate

简化分子线性输入规范(SMILES)

O=C(OC1=CC=C(N=C(C(N2C3)=CC(C(CC)(O)OC4)=C4C2=O)C3=C5CC)C5=C1)N(CC6)CCC6N7CCCCC7

分子式

C32H38N4O5

分子量

558.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan Impurity 2 is chemically 3,10-Diethyl-3-hydroxy-13-oxo-11,13-dihydro-1H,3H-furo[3′,4′:6,7]indolizino[1,2-b]quinolin-8-yl [1,4′-bipiperidine]-1′-carboxylate. Irinotecan Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-impurity-2-cas-143490-54-4/

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Irinotecan 杂质 5 CAS号 2656-50-0

基本信息

CAS(化学文摘登记)号

2656-50-0

英文名称

Irinotecan 杂质 5

英文化学名

1-(2-Amino-5-hydroxyphenyl)ethan-1-one hydrochloride

简化分子线性输入规范(SMILES)

CC(C(C=C(O)C=C1)=C1N)=O.Cl

分子式

C8H9NO2 : HCl

分子量

151.2 : 18.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan Impurity 5 is chemically 1-(2-Amino-5-hydroxyphenyl)ethan-1-one hydrochloride. Irinotecan Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-impurity-5-cas-2656-50-0/

相关产品

30954-71-3 (游离碱)

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Irinotecan EP 杂质 A CAS号 158406-44-1

基本信息

CAS(化学文摘登记)号

158406-44-1

英文名称

Irinotecan EP 杂质 A

英文化学名

(4S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride trihydrate (as per EP);(S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride trihydrate (as per USP)

简化分子线性输入规范(SMILES)

O[C@@](C(OC1)=O)(CC)C2=C1C(N3C(C4=NC5=CC=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C5C=C4C3)=C2)=O.[3H2O].Cl

分子式

C31H34N4O6 : HCl : 3(H2O)

分子量

558.6 : 36.5 : 3(18.0)

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan EP Impurity A is chemically (4S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride trihydrate (as per EP);(S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride trihydrate (as per USP). It is also known as 11-Desethyl Irinotecan (as per EP). Irinotecan EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-ep-impurity-a-cas-158406-44-1/

相关产品

103816-16-6 (游离碱) ; 207683-84-9 (盐酸盐) ; 883718-83-0 (硫酸盐)

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Irinotecan EP Impurity C CAS号 947687-02-7

基本信息

CAS(化学文摘登记)号

947687-02-7

英文名称

Irinotecan EP Impurity C

英文化学名

(S)-4,8,11-Triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate

简化分子线性输入规范(SMILES)

O[C@@](C(OC1)=O)(CC)C2=C1C(N3C(C4=NC5=CC(CC)=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C5C(CC)=C4C3)=C2)=O

分子式

C35H42N4O6

分子量

614.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan EP Impurity C is chemically (S)-4,8,11-Triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate. It is also known as Irinotecan 11-Ethyl Impurity (USP). Irinotecan EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan11-ethyl-impurity-usp-cas-947687-02-7/

相关产品

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Irinotecan Lactone Impurity CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Irinotecan Lactone Impurity

英文化学名

1-(1-(((3,10-Diethyl-1,13-dioxo-11,13-dihydro-1H,3H-furo[3′,4′:6,7]indolizino[1,2-b]quinolin-8-yl)oxy)carbonyl)piperidin-4-yl)piperidin-1-ium chloride

简化分子线性输入规范(SMILES)

O=C(OC1=CC=C(N=C(C(N2C3)=CC(C(CC)OC4=O)=C4C2=O)C3=C5CC)C5=C1)N(CC6)CCC6[NH+]7CCCCC7.[Cl-]

分子式

C32H37N4O5 : Cl

分子量

557.7 : 35.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan Lactone Impurity is chemically 1-(1-(((3,10-Diethyl-1,13-dioxo-11,13-dihydro-1H,3H-furo[3′,4′:6,7]indolizino[1,2-b]quinolin-8-yl)oxy)carbonyl)piperidin-4-yl)piperidin-1-ium chloride. Irinotecan Lactone Impurity is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Lactone Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-lactone-impurity-cas-N/A/

相关产品

143490-53-3 (free base)

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Irinotecan EP Impurity M (TFA Salt) CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Irinotecan EP Impurity M (TFA Salt)

英文化学名

(4S)-4,11-Diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate 2,2,2-trifluoroacetate

简化分子线性输入规范(SMILES)

OC(C(C1=NC2=CC=C(OC(N3CCC(N4CCCCC4)CC3)=O)C=C52)=C5CC)N6C1=CC([C@](O)7CC)=C(COC7=O)C6=O.O=C(O)C(F)(F)F

分子式

C33H38N4O7 : C2HF3O2

分子量

602.7 : 114.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan EP Impurity M (TFA Salt) is chemically (4S)-4,11-Diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate 2,2,2-trifluoroacetate. It is also known as 12-Hydroxy Irinotecan. Irinotecan EP Impurity M (TFA Salt) is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity M (TFA Salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-ep-impurity-m-tfa-salt-cas-N/A/

相关产品

185336-12-3 (free base)

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Irinotecan Keto Impurity CAS号 176515-52-9

基本信息

CAS(化学文摘登记)号

176515-52-9

英文名称

Irinotecan Keto Impurity

英文化学名

12-Ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4′-bipiperidine]-1′-carboxylate

简化分子线性输入规范(SMILES)

O=C(C(C=C(C1=NC2=CC=C(C=C32)OC(N4CCC(CC4)N5CCCCC5)=O)N6CC1=C3CC)=C(C6=O)C)CC

分子式

C32H38N4O4

分子量

542.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan Keto Impurity is chemically 12-Ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4′-bipiperidine]-1′-carboxylate. Irinotecan Keto Impurity is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Keto Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecanketo-impurity-cas-176515-52-9/

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Irinotecan EP Impurity G CAS号 947687-01-6

基本信息

CAS(化学文摘登记)号

947687-01-6

英文名称

Irinotecan EP Impurity G

英文化学名

(4S)-4,8,11-triethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per EP);(S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per USP)

简化分子线性输入规范(SMILES)

O=C1C2=C([C@@](O)(CC)C(OC2)=O)C=C3C4=NC5=CC(CC)=C(O)C=C5C(CC)=C4CN31

分子式

C24H24N2O5

分子量

420.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan EP Impurity G is chemically (4S)-4,8,11-triethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per EP);(S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per USP). It is also known as 7,11-Diethyl-10-hydroxy camptothecin. Irinotecan EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecan-ep-impurity-g-cas-947687-01-6/

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Irinotecan EP Impurity E CAS号 86639-52-3

基本信息

CAS(化学文摘登记)号

86639-52-3

英文名称

Irinotecan EP Impurity E

英文化学名

(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per EP);(S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per USP)

简化分子线性输入规范(SMILES)

O[C@@](C(OC1)=O)(CC)C2=C1C(N3C(C4=NC5=CC=C(O)C=C5C(CC)=C4C3)=C2)=O

分子式

C22H20N2O5

分子量

392.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Irinotecan EP Impurity E is chemically (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per EP);(S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (as per USP). It is also known as Irinotecan USP Related Compound B. Irinotecan EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/irinotecanusp-rc-b-cas-86639-52-3/

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