文章

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Eltrombopag Lactose Adduct

英文化学名

(3R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl 3′-(2-((Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylate

简化分子线性输入规范(SMILES)

OC(C(N/N=C1C(N(C2=CC=C(C)C(C)=C2)N=C1C)=O)=CC=C3)=C3C4=CC(C(OC5O[C@H](CO)[C@@H](O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O)[C@H]6O)C(O)[C@H]5O)=O)=CC=C4

分子式

C37H42N4O14

分子量

766.8

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag Lactose Adduct is chemically (3R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl 3′-(2-((Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylate. Eltrombopag Lactose Adduct is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag Lactose Adduct can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-lactose-adduct-cas-N/A/

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基本信息

CAS(化学文摘登记)号

277299-70-4

英文名称

Eltrombopag  Pyrazole 杂质

英文化学名

2-(3,4-Dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one

简化分子线性输入规范(SMILES)

CC1=CC=C(N2NC(C)=CC2=O)C=C1C

分子式

C12H14N2O

分子量

202.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag  Pyrazole Impurity is chemically 2-(3,4-Dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one. Eltrombopag  Pyrazole Impurity is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag  Pyrazole Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-pyrazole-impurity-cas-277299-70-4/

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基本信息

CAS(化学文摘登记)号

193979-22-5

英文名称

Eltrombopag Lactose Olamine Adduct

英文化学名

(2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6S)-4,5-Dihydroxy-6-((2-hydroxyethyl)amino)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

简化分子线性输入规范(SMILES)

O[C@H]1[C@@H](NCCO)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

分子式

C14H27NO11

分子量

385.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag Lactose Olamine Adduct is chemically (2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6S)-4,5-Dihydroxy-6-((2-hydroxyethyl)amino)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Eltrombopag Lactose Olamine Adduct is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag Lactose Olamine Adduct can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-lactose-olamine-adduct-cas-193979-22-5/

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基本信息

CAS(化学文摘登记)号

376592-93-7

英文名称

Eltrombopag Amino 杂质

英文化学名

3′-Amino-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid

简化分子线性输入规范(SMILES)

NC1=C(O)C(C2=CC=CC(C(O)=O)=C2)=CC=C1

分子式

C13H11NO3

分子量

229.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag Amino Impurity is chemically 3′-Amino-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid. Eltrombopag Amino Impurity is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag Amino Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-amino-impurity-cas-376592-93-7/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Eltrombopag  Methoxy 杂质

英文化学名

2-Aminoethyl (Z)-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2′-methoxy-[1,1′-biphenyl]-3-carboxylate 2,2,2-trifluoroacetate

简化分子线性输入规范(SMILES)

NCCOC(C1=CC(C2=CC=CC(N/N=C3C(N(C4=CC=C(C)C(C)=C4)N=C3C)=O)=C2OC)=CC=C1)=O.O=C(O)C(F)(F)F

分子式

C28H29N5O4 : C2HF3O2

分子量

499.6 : 114.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag  Methoxy Impurity is chemically 2-Aminoethyl (Z)-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2′-methoxy-[1,1′-biphenyl]-3-carboxylate 2,2,2-trifluoroacetate. Eltrombopag  Methoxy Impurity is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag  Methoxy Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-methoxy-impurity-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Eltrombopag 杂质 9

英文化学名

(Z)-5′-Chloro-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid

简化分子线性输入规范(SMILES)

ClC1=CC(N(O)/N=C2C(N(C3=CC=C(C)C(C)=C3)N=C2C)=O)=C(O)C(C4=CC=CC(C(O)=O)=C4)=C1

分子式

C25H21ClN4O5

分子量

492.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag Impurity 9 is chemically (Z)-5′-Chloro-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid. Eltrombopag Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-impurity-9-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Eltrombopag 杂质 2

英文化学名

(Z)-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid

简化分子线性输入规范(SMILES)

CC1=C(C)C=C(N2N=C(C)/C(C2=O)=N/N(C3=CC=CC(C4=CC(C(O)=O)=CC=C4)=C3O)N=O)C=C1

分子式

C25H21N5O5

分子量

471.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Eltrombopag Impurity 2 is chemically (Z)-3′-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid. N-Nitroso Eltrombopag Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Eltrombopag Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱:chemwhat@watson-int.cn

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ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/n-nitroso-eltrombopag-impurity-2-cas-N/A/

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基本信息

CAS(化学文摘登记)号

496775-61-2

英文名称

Eltrombopag

英文化学名

3’-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2’-hydroxy-[1,1’-biphenyl]-3-carboxylic acid; SB 497115

简化分子线性输入规范(SMILES)

O=C1N(C2=CC(C)=C(C)C=C2)N=C(C)/C1=N/NC(C=CC=C3C4=CC(C(O)=O)=CC=C4)=C3O

分子式

C25H22N4O4

分子量

442.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag is chemically 3’-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2’-hydroxy-[1,1’-biphenyl]-3-carboxylic acid; SB 497115. Eltrombopag is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-cas-496775-61-2/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Eltrombopag 相关化合物

英文化学名

N-Acetyl -SB-611855 Glucuronide

简化分子线性输入规范(SMILES)

OC([C@H]([C@H]([C@@H]1O)O)OC(OC2=C(C3=CC=CC(C(O)=O)=C3)C=CC=C2NC(C)=O)[C@@H]1O)=O

分子式

C21H21NO10

分子量

447.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag Related Compound is chemically N-Acetyl -SB-611855 Glucuronide. Eltrombopag Related Compound is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag Related Compound can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-related-compound-cas-N/A/

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Eltrombopag N-Oxide 杂质 (E-Isomer)

英文化学名

(E)-3′-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid

简化分子线性输入规范(SMILES)

O=C1N(C2=CC(C)=C(C)C=C2)N=C(C)/C1=NN(O)C3=C(O)C(C4=CC(C(O)=O)=CC=C4)=CC=C3

分子式

C25H22N4O5

分子量

458.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁;质谱,液相色谱

保存条件

常温避光保存

产品描述

Eltrombopag N-Oxide Impurity (E-Isomer) is chemically (E)-3′-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid. It is also known as Eltrombopag N-Hydroxy Impurity. Eltrombopag N-Oxide Impurity (E-Isomer) is supplied with detailed characterization data compliant with regulatory guideline. Eltrombopag N-Oxide Impurity (E-Isomer) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Eltrombopag. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱:chemwhat@watson-int.cn

品牌

ChemWhat(凯望)—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/eltrombopag-n-oxide-impurity-cas-N/A/

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