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Dolutegravir 杂质 18 CAS号 2710626-41-6

基本信息

CAS(化学文摘登记)号

2710626-41-6

英文名称

Dolutegravir 杂质 18

英文化学名

2-[(2R)-4-Hydroxybutan-2-yl]-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid

简化分子线性输入规范(SMILES)

O=C(C1=CN2C(C(N([C@@H](CCO)C)C=C2)=O)=C(OC)C1=O)O

分子式

C14H16N2O6

分子量

308.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Impurity 18 is chemically 2-[(2R)-4-Hydroxybutan-2-yl]-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid. Dolutegravir Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-impurity-18-cas-2710626-41-6/

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Dolutegravir 杂质 15 CAS号 1973402-05-9

基本信息

CAS(化学文摘登记)号

1973402-05-9

英文名称

Dolutegravir 杂质 15

英文化学名

(R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide

简化分子线性输入规范(SMILES)

FC1=CC=C(CNC(C2=CN(C=CN([C@H](C)CCO)C3=O)C3=C(O)C2=O)=O)C(F)=C1

分子式

C20H19F2N3O5

分子量

419.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Impurity 15 is chemically (R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide. Dolutegravir Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-impurity-15-cas-1973402-05-9/

相关产品

2769753-77-5 (sodium salt)

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4-Fluoro Dolutegravir (sodium salt) CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

4-Fluoro Dolutegravir (sodium salt)

英文化学名

Sodium (4R,12aS)-9-((4-fluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazin-7-olate

简化分子线性输入规范(SMILES)

FC1=CC=C(CNC(C2=CN(C[C@@](OCC[C@]3(C)[H])([H])N3C4=O)C4=C([O-])C2=O)=O)C=C1.[Na+]

分子式

C20H19FN3O5 : Na

分子量

400.4 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

4-Fluoro Dolutegravir (sodium salt) is chemically Sodium (4R,12aS)-9-((4-fluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazin-7-olate. 4-Fluoro Dolutegravir (sodium salt) is supplied with detailed characterization data compliant with regulatory guideline. 4-Fluoro Dolutegravir (sodium salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/4-fluoro-dolutegravir-sodium-salt-cas-N/A/

相关产品

1863916-88-4 (游离碱)

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4-Epi-Dolutegravir CAS号 1357289-37-2

基本信息

CAS(化学文摘登记)号

1357289-37-2

英文名称

4-Epi-Dolutegravir

英文化学名

(4S,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

简化分子线性输入规范(SMILES)

FC1=CC=C(CNC(C2=CN(C[C@@](OCC[C@@H]3C)([H])N3C4=O)C4=C(O)C2=O)=O)C(F)=C1

分子式

C20H19F2N3O5

分子量

419.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

4-Epi-Dolutegravir is chemically (4S,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide. It is also known as Dolutegravir SS Isomer. 4-Epi-Dolutegravir is supplied with detailed characterization data compliant with regulatory guideline. 4-Epi-Dolutegravir can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/4-epi-dolutegravir-cas-1357289-37-2/

相关产品

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4-Desfluoro-6-Fluoro Dolutegravir (sodium salt) CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

4-Desfluoro-6-Fluoro Dolutegravir (sodium salt)

英文化学名

Sodium (4R,12aS)-9-((2,6-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazin-7-olate

简化分子线性输入规范(SMILES)

O=C1C([O-])=C2N(C[C@@](OCC[C@]3(C)[H])([H])N3C2=O)C=C1C(NCC4=C(F)C=CC=C4F)=O.[Na+]

分子式

C20H18F2N3O5 : Na

分子量

418.4 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

4-Desfluoro-6-Fluoro Dolutegravir (sodium salt) is chemically Sodium (4R,12aS)-9-((2,6-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazin-7-olate. 4-Desfluoro-6-Fluoro Dolutegravir (sodium salt) is supplied with detailed characterization data compliant with regulatory guideline. 4-Desfluoro-6-Fluoro Dolutegravir (sodium salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/4-desfluoro-6-fluoro-dolutegravir-sodium-salt-cas-N/A/

相关产品

2244161-72-4 (游离碱)

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Dolutegravir 杂质 6 CAS号 2769753-77-5

基本信息

CAS(化学文摘登记)号

2769753-77-5

英文名称

Dolutegravir 杂质 6

英文化学名

Sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-9-olate

简化分子线性输入规范(SMILES)

OCC[C@@H](C)N(C1=O)C=CN(C1=C([O-])C2=O)C=C2C(NCC3=C(F)C=C(F)C=C3)=O.[Na+]

分子式

C20H18F2N3O5 : Na

分子量

418.4 : 23.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Impurity 6 is chemically Sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-9-olate. Dolutegravir Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-impurity-6-cas-2769753-77-5/

相关产品

1973402-05-9 (游离碱)

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Dolutegravir 杂质 8 CAS号 1916490-96-4

基本信息

CAS(化学文摘登记)号

1916490-96-4

英文名称

Dolutegravir 杂质 8

英文化学名

(E)-N-(2,4-Difluorobenzyl)-1-(2,4-difluorophenyl)methanimine

简化分子线性输入规范(SMILES)

FC1=C(C=CC(F)=C1)C/N=C/C(C=CC(F)=C2)=C2F

分子式

C14H9F4N

分子量

267.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Impurity 8 is chemically (E)-N-(2,4-Difluorobenzyl)-1-(2,4-difluorophenyl)methanimine. Dolutegravir Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-impurity-8-cas-1916490-96-4/

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Dolutegravir D6 CAS号 1407167-38-7

基本信息

CAS(化学文摘登记)号

1407167-38-7

英文名称

Dolutegravir D6

英文化学名

(4R,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-(methyl-d3)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-4,12,12-d3-9-carboxamide

简化分子线性输入规范(SMILES)

O=C(N([C@]1([2H])C([2H])([2H])[2H])[C@](OCC1)([H])C([2H])([2H])N2C=C(C(NCC(C=CC(F)=C3)=C3F)=O)C4=O)C2=C4O

分子式

C20H13D6F2N3O5

分子量

425.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir D6 is chemically (4R,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-(methyl-d3)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-4,12,12-d3-9-carboxamide. Dolutegravir D6 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir D6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-d6-cas-1407167-38-7/

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Dolutegravir Oxidative Degradation product B CAS号 1248263-78-6

基本信息

CAS(化学文摘登记)号

1248263-78-6

英文名称

Dolutegravir Oxidative Degradation product B

英文化学名

2-((2,4-Difluorobenzyl)amino)-2-oxoacetic acid

简化分子线性输入规范(SMILES)

O=C(O)C(NCC1=CC=C(F)C=C1F)=O

分子式

C9H7F2NO3

分子量

215.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Oxidative Degradation product B is chemically 2-((2,4-Difluorobenzyl)amino)-2-oxoacetic acid. Dolutegravir Oxidative Degradation product B is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Oxidative Degradation product B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-oxidative-degradation-product-b-cas-1248263-78-6/

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Dolutegravir 杂质 12 CAS号 1802141-49-6

基本信息

CAS(化学文摘登记)号

1802141-49-6

英文名称

Dolutegravir 杂质 12

英文化学名

(4R,12aS)-N-(2,4-Difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

简化分子线性输入规范(SMILES)

FC1=CC(F)=C(CNC(C2=CN(C[C@@](OCC[C@H]3C)([H])N3C4=O)C4=C(OCC)C2=O)=O)C=C1

分子式

C22H23F2N3O5

分子量

447.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Dolutegravir Impurity 12 is chemically (4R,12aS)-N-(2,4-Difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide. Dolutegravir Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Dolutegravir Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dolutegravir. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/dolutegravir-impurity-12-cas-1802141-49-6/

相关产品

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