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Cabozantinib Desmethyl 杂质 1 CAS号 1628530-42-6

基本信息

CAS(化学文摘登记)号

1628530-42-6

英文名称

Cabozantinib Desmethyl 杂质 1

英文化学名

N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

简化分子线性输入规范(SMILES)

O=C(C1(CC1)C(NC(C=C2)=CC=C2F)=O)NC(C=C3)=CC=C3OC4=CC=NC(C=C5O)=C4C=C5OC

分子式

C27H22FN3O5

分子量

487.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Desmethyl Impurity 1 is chemically N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide. Cabozantinib Desmethyl Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Desmethyl Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-desmethyl-impurity-1-cas-1628530-42-6/

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Cabozantinib Urea Dimer CAS号 2840522-81-6

基本信息

CAS(化学文摘登记)号

2840522-81-6

英文名称

Cabozantinib Urea Dimer

英文化学名

1,3-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)urea

简化分子线性输入规范(SMILES)

O=C(NC1=CC=C(OC2=CC=NC3=CC(OC)=C(OC)C=C23)C=C1)NC4=CC=C(OC5=CC=NC6=CC(OC)=C(OC)C=C56)C=C4

分子式

C35H30N4O7

分子量

618.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Urea Dimer is chemically 1,3-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)urea. Cabozantinib Urea Dimer is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Urea Dimer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-urea-dimer-cas-2840522-81-6/

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Cabozantinib-D6 CAS号 1802168-46-2

基本信息

CAS(化学文摘登记)号

1802168-46-2

英文名称

Cabozantinib-D6

英文化学名

N-(4-((6,7-Bis(methoxy-d3)quinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

简化分子线性输入规范(SMILES)

O=C(C1(CC1)C(NC(C=C2)=CC=C2F)=O)NC(C=C3)=CC=C3OC4=CC=NC(C=C5OC([2H])([2H])[2H])=C4C=C5OC([2H])([2H])[2H]

分子式

C28H18D6FN3O5

分子量

507.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib-D6 is chemically N-(4-((6,7-Bis(methoxy-d3)quinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide. Cabozantinib-D6 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib-D6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-d6-cas-1802168-46-2/

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Cabozantinib 杂质 23 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Cabozantinib 杂质 23

英文化学名

N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide

简化分子线性输入规范(SMILES)

O=C(NC1=CC=C(OC2=CC=NC3=CC(OC)=C(OC)C=C23)C=C1)C(CCO)C(NC4=CC=C(F)C=C4)=O

分子式

C28H26FN3O6

分子量

519.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 23 is chemically N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide. Cabozantinib Impurity 23 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 23 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinibimpurity-23-cas-N/A/

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Cabozantinib 杂质 13 CAS号 1355031-15-0

基本信息

CAS(化学文摘登记)号

1355031-15-0

英文名称

Cabozantinib 杂质 13

英文化学名

4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol

简化分子线性输入规范(SMILES)

OC1=C(OC)C=C2C(OC3=CC=C(N)C=C3)=CC=NC2=C1

分子式

C16H14N2O3

分子量

282.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 13 is chemically 4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol. Cabozantinib Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-impurity-13-cas-1355031-15-0/

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Cabozantinib 杂质 15 CAS号 213699-53-7

基本信息

CAS(化学文摘登记)号

213699-53-7

英文名称

Cabozantinib 杂质 15

英文化学名

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

简化分子线性输入规范(SMILES)

O=C(OC(C)(C)O1)/C(C1=O)=C/NC2=CC(OC)=C(OC)C=C2

分子式

C15H17NO6

分子量

307.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 15 is chemically 5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione. Cabozantinib Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-impurity-15-cas-213699-53-7/

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Cabozantinib 杂质 21 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Cabozantinib 杂质 21

英文化学名

(2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic acid

简化分子线性输入规范(SMILES)

COC1=C(C=C(N=CC=C2OC3=CC=C(NC(C(CCOC(C[C@H](O)C(O)=O)=O)C(NC4=CC=C(F)C=C4)=O)=O)C=C3)C2=C1)OC

分子式

C32H30FN3O10

分子量

635.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 21 is chemically (2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic acid. Cabozantinib Impurity 21 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 21 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinibimpurity-21-cas-N/A/

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Cabozantinib 杂质 18 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Cabozantinib 杂质 18

英文化学名

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide

简化分子线性输入规范(SMILES)

O=C(C1(C(N)=O)CC1)N(C2=CC=C(OC3=CC=NC4=CC(OC)=C(OC)C=C34)C=C2)C5=CC=CC(F)=C5

分子式

C28H24FN3O5

分子量

501.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 18 is chemically N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide. Cabozantinib Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinibimpurity-18-cas-N/A/

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Cabozantinib 杂质 16 CAS号 2439164-91-5

基本信息

CAS(化学文摘登记)号

2439164-91-5

英文名称

Cabozantinib 杂质 16

英文化学名

N,N’-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

简化分子线性输入规范(SMILES)

O=C(C1(CC1)C(NC2=CC=C(OC3=CC=NC4=C3C=C(OC)C(OC)=C4)C=C2)=O)NC5=CC=C(OC6=CC=NC7=C6C=C(OC)C(OC)=C7)C=C5

分子式

C39H34N4O8

分子量

686.7

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 16 is chemically N,N’-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide. Cabozantinib Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-impurity-16-cas-2439164-91-5/

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Cabozantinib 杂质 17 CAS号 3697-66-3

基本信息

CAS(化学文摘登记)号

3697-66-3

英文名称

Cabozantinib 杂质 17

英文化学名

1-(Ethoxycarbonyl)cyclopropane-1-carboxylic acid

简化分子线性输入规范(SMILES)

O=C(C1(CC1)C(O)=O)OCC

分子式

C7H10O4

分子量

158.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Cabozantinib Impurity 17 is chemically 1-(Ethoxycarbonyl)cyclopropane-1-carboxylic acid. Cabozantinib Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Cabozantinib Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabozantinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/cabozantinib-impurity-17-cas-3697-66-3/

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