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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Bleomycin 杂质 5

英文化学名

((2R,3S,4S,5R,6S)-2-(((2R,3S,4S,5S,6S)-2-(2-(6-amino-2-(1,3-diamino-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-((5-((1-((2-(4-((4-guanidinobutyl)carbamoyl)-[2,5′-bithiazol]-2′-yl)ethyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-4-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)carbamate

简化分子线性输入规范(SMILES)

分子式

C52H77N18O20S2

分子量

1338.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Bleomycin Impurity 5 is chemically ((2R,3S,4S,5R,6S)-2-(((2R,3S,4S,5S,6S)-2-(2-(6-amino-2-(1,3-diamino-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-((5-((1-((2-(4-((4-guanidinobutyl)carbamoyl)-[2,5′-bithiazol]-2′-yl)ethyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-4-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)carbamate. Bleomycin Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Bleomycin Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bleomycin Sulfate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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• 基本信息
• 物理性质
• 安全信息
• 详细规格
• 快速询价及关联信息

基本信息

CAS(化学文摘登记)号

11056-06-7

英文名称

Bleomycin

英文化学名

(3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium

简化分子线性输入规范(SMILES)

O[C@H]1[C@H](OC(N)=O)[C@H](O)[C@@H](O[C@H]2[C@@H](O)[C@H](O)[C@H](CO)O[C@H]2OC([C@H](NC(C3=NC([C@@H](NC[C@H](N)C(N)=O)CC(N)=O)=NC(N)=C3C)=O)C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC4=NC(C5=NC(C(NCCC[S+](C)C)=O)=CS5)=CS4)=O)=O)=O)C6=CNC=N6)O[C@@H]1CO

分子式

C55H84N17O21S3

分子量

1415.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Bleomycin is chemically (3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium. Bleomycin is supplied with detailed characterization data compliant with regulatory guideline. Bleomycin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bleomycin Sulfate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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9041-93-4 (硫酸盐)

• 基本信息
• 物理性质
• 安全信息
• 详细规格
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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Bleomycin 杂质 6

英文化学名

(3-(2′-(1-(6-Amino-2-(3-amino-1-((2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-7-hydroxy-3-(hydroxy(1H-imidazol-4-yl)methyl)-11-(1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,5′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium

简化分子线性输入规范(SMILES)

C[S+](CCCNC(C1=CSC(C2=CN=C(CCNC(C(NC(C(C)C(O)C(NC(C(NC(C3=NC(C(NCC(N)C(N)=O)CC(N)=O)=NC(N)=C3C)=O)C(O)C4=CNC=N4)=O)C)=O)C(O)C)=O)S2)=N1)=O)C

分子式

C42H63N16O10S3

分子量

1048.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Bleomycin Impurity 6 is chemically (3-(2′-(1-(6-Amino-2-(3-amino-1-((2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-7-hydroxy-3-(hydroxy(1H-imidazol-4-yl)methyl)-11-(1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,5′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium. Bleomycin Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Bleomycin Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bleomycin Sulfate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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基本信息

CAS(化学文摘登记)号

N/A

英文名称

N-Nitroso Bleomycin

英文化学名

(3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)(nitroso)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium

简化分子线性输入规范(SMILES)

O[C@H]1[C@H](OC(N)=O)[C@H](O)[C@@H](O[C@H]2[C@@H](O)[C@H](O)[C@H](CO)O[C@H]2OC([C@H](NC(C3=NC([C@@H](N(N=O)C[C@H](N)C(N)=O)CC(N)=O)=NC(N)=C3C)=O)C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC4=NC(C5=NC(C(NCCC[S+](C)C)=O)=CS5)=CS4)=O)=O)=O)C6=CNC=N6)O[C@@H]1CO

分子式

C55H83N18O22S3

分子量

1444.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

N-Nitroso Bleomycin is chemically (3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)(nitroso)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium. N-Nitroso Bleomycin is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Bleomycin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bleomycin Sulfate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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• 详细规格
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基本信息

CAS(化学文摘登记)号

N/A

英文名称

Bleomycin 杂质 2

英文化学名

(3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-(3-amino-1-(((S)-3-amino-2-(isopropylamino)-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((R)-(((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6S)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((S)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,5′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium

简化分子线性输入规范(SMILES)

NC1=NC(C(CC(N)=O)NC[C@@](NC(C)C)([H])C(N)=O)=NC(C(N[C@@](C(N[C@]([C@](O)([H])[C@@](C)([H])C(N[C@]([C@](O)([H])C)([H])C(NCCC2=NC=C(C3=NC(C(NCCC[S+](C)C)=O)=CS3)S2)=O)=O)([H])C)=O)([H])[C@](O[C@H]4[C@@H](O[C@@H]5[C@@H](O)[C@@H](OC(N)=O)[C@H](O)[C@H](CO)O5)[C@@H](O)[C@H](O)[C@H](CO)O4)([H])C6=CNC=N6)=O)=C1C

分子式

C58H90N17O21S3

分子量

1457.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Bleomycin Impurity 2 is chemically (3-(2′-((3S,6R,7S,8S,11S)-1-(6-Amino-2-(3-amino-1-(((S)-3-amino-2-(isopropylamino)-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((R)-(((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6S)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((S)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,5′-bithiazole]-4-carboxamido)propyl)dimethylsulfonium. Bleomycin Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Bleomycin Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bleomycin Sulfate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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