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Apixaban Isopropyl Ester 杂质 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Apixaban Isopropyl Ester 杂质

英文化学名

4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester

简化分子线性输入规范(SMILES)

O=C1CCCCN1C2=CC=C(N3CCC(C(C(OC(C)C)=O)=NN4C5=CC=C(OC)C=C5)=C4C3=O)C=C2

分子式

C28H30N4O5

分子量

502.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Isopropyl Ester Impurity  is chemically 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester . Apixaban Isopropyl Ester Impurity  is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Isopropyl Ester Impurity  can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixabanisopropyl-ester-impurity-cas-N/A/

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Apixaban 杂质 42 CAS号 1609409-54-2

基本信息

CAS(化学文摘登记)号

1609409-54-2

英文名称

Apixaban 杂质 42

英文化学名

2-(5-Hydroxy-6-oxo-1-(4-(2-oxopiperidin-1-yl)phenyl)-1,2,3,6-tetrahydropyridin-4-yl)-2-oxoacetic acid

简化分子线性输入规范(SMILES)

O=C1CCCCN1C2=CC=C(N3CCC(C(C(O)=O)=O)=C(O)C3=O)C=C2

分子式

C18H18N2O6

分子量

358.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity 42 is chemically 2-(5-Hydroxy-6-oxo-1-(4-(2-oxopiperidin-1-yl)phenyl)-1,2,3,6-tetrahydropyridin-4-yl)-2-oxoacetic acid. Apixaban Impurity 42 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 42 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

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ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-42-cas-1609409-54-2/

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Apixaban 杂质 C CAS号 1904628-10-9

基本信息

CAS(化学文摘登记)号

1904628-10-9

英文名称

Apixaban 杂质 C

英文化学名

2-Hydroxyethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

简化分子线性输入规范(SMILES)

O=C1CCCCN1C2=CC=C(N3CCC(C(C(OCCO)=O)=NN4C5=CC=C(OC)C=C5)=C4C3=O)C=C2

分子式

C27H28N4O6

分子量

504.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity C is chemically 2-Hydroxyethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate. Apixaban Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-c-cas-1904628-10-9/

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Apixaban Chloro 杂质 CAS号 2029205-64-7

基本信息

CAS(化学文摘登记)号

2029205-64-7

英文名称

Apixaban Chloro 杂质

英文化学名

1-(4-Chlorophenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1Hpyrazolo[3,4-c] pyridine-3-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=NN(C2=CC=C(Cl)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)N

分子式

C24H22ClN5O3

分子量

463.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Chloro Impurity is chemically 1-(4-Chlorophenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1Hpyrazolo[3,4-c] pyridine-3-carboxamide. It is also known as Apixaban Chloro Impurity. Apixaban Chloro Impurity is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Chloro Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-chloro-impurity-cas-2029205-64-7/

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Apixaban 杂质 41 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Apixaban 杂质 41

英文化学名

(5S)-N-(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)-5-chloro-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-6-carboxamide

简化分子线性输入规范(SMILES)

O=C(C1=NN(C2=CC=C(OC)C=C2)C3=C1CCN(C4=CC=C(NC(C5C(N6CCS[C@@]65Cl)=O)=O)C=C4)C3=O)N

分子式

C26H23ClN6O5S

分子量

567.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity 41 is chemically (5S)-N-(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)-5-chloro-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-6-carboxamide. Apixaban Impurity 41 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 41 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-41-cas-N/A/

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Apixaban 杂质 E CAS号 1609409-53-1

基本信息

CAS(化学文摘登记)号

1609409-53-1

英文名称

Apixaban 杂质 E

英文化学名

Ethyl{5-hydroxy-6-oxo-1-[4-(2-oxopiperidin-1-yl)phenyl]-1,2,3,6-tetrahydropyridin-4-yl}(oxo)acetate

简化分子线性输入规范(SMILES)

O=C(OCC)C(C(CCN1C2=CC=C(N3C(CCCC3)=O)C=C2)=C(O)C1=O)=O

分子式

C20H22N2O6

分子量

386.4

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity E is chemically Ethyl{5-hydroxy-6-oxo-1-[4-(2-oxopiperidin-1-yl)phenyl]-1,2,3,6-tetrahydropyridin-4-yl}(oxo)acetate. Apixaban Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-e-cas-1609409-53-1/

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Apixaban 杂质 38 CAS号 1998079-13-2

基本信息

CAS(化学文摘登记)号

1998079-13-2

英文名称

Apixaban 杂质 38

英文化学名

(E)-Diethyl 6,6’-(diazene-1,2-diylbis(4,1-phenylene))bis(1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate)

简化分子线性输入规范(SMILES)

O=C(N(C1=CC=C(/N=N/C2=CC=C(N(CCC3=C4N(C5=CC=C(OC)C=C5)N=C3C(OCC)=O)C4=O)C=C2)C=C1)CC6)C7=C6C(C(OCC)=O)=NN7C8=CC=C(OC)C=C8

分子式

C44H40N8O8

分子量

808.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity 38 is chemically (E)-Diethyl 6,6’-(diazene-1,2-diylbis(4,1-phenylene))bis(1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate). Apixaban Impurity 38 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 38 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-38-cas-1998079-13-2/

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Apixaban 杂质 39 CAS号 1998079-14-3

基本信息

CAS(化学文摘登记)号

1998079-14-3

英文名称

Apixaban 杂质 39

英文化学名

(Z)-1,2-Bis(4-(3-(ethoxycarbonyl)-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)diazene 1-oxide

简化分子线性输入规范(SMILES)

O=C(N(C1=CC=C(N=[N](C2=CC=C(N(CCC3=C4N(C5=CC=C(OC)C=C5)N=C3C(OCC)=O)C4=O)C=C2)=O)C=C1)CC6)C7=C6C(C(OCC)=O)=NN7C8=CC=C(OC)C=C8

分子式

C44H40N8O9

分子量

824.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity 39 is chemically (Z)-1,2-Bis(4-(3-(ethoxycarbonyl)-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)diazene 1-oxide. Apixaban Impurity 39 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 39 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-39-cas-1998079-14-3/

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Apixaban 13C D3 CAS号 1261393-15-0

基本信息

CAS(化学文摘登记)号

1261393-15-0

英文名称

Apixaban 13C D3

英文化学名

1-[4-2-Oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3boxamide

简化分子线性输入规范(SMILES)

O=C(N(C1=CC=C(N(CCCC2)C2=O)C=C1)CC3)C4=C3C(C(N)=O)=NN4C5=CC=C(O[13C]([2H])([2H])[2H])C=C5

分子式

C2413CH22D3N5O4

分子量

463.5

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban 13C D3 is chemically 1-[4-2-Oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3boxamide. Apixaban 13C D3 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban 13C D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-13c-d3-cas-1261393-15-0/

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Apixaban 杂质 43 CAS号 1998079-15-4

基本信息

CAS(化学文摘登记)号

1998079-15-4

英文名称

Apixaban 杂质 43

英文化学名

(E)-1,1′-(Diazene-1,2-diylbis(4,1-phenylene))bis(3-morpholino-5,6-dihydropyridin-2(1H)-one)

简化分子线性输入规范(SMILES)

O=C1C(N2CCOCC2)=CCCN1C(C=C3)=CC=C3/N=N/C(C=C4)=CC=C4N5C(C(N6CCOCC6)=CCC5)=O

分子式

C30H34N6O4

分子量

542.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Apixaban Impurity 43 is chemically (E)-1,1′-(Diazene-1,2-diylbis(4,1-phenylene))bis(3-morpholino-5,6-dihydropyridin-2(1H)-one). Apixaban Impurity 43 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 43 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/apixaban-impurity-43-cas-1998079-15-4/

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