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Afatinib 杂质 34 CAS号 16499-57-3

基本信息

CAS(化学文摘登记)号

16499-57-3

英文名称

Afatinib 杂质 34

英文化学名

7-Fluoroquinazolin-4(3H)-one

简化分子线性输入规范(SMILES)

O=C1NC=NC2=C1C=CC(F)=C2

分子式

C8H5FN2O

分子量

164.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 34 is chemically 7-Fluoroquinazolin-4(3H)-one. Afatinib Impurity 34 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 34 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

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邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-34-cas-16499-57-3/

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Afatinib 杂质 37 CAS号 2223677-61-8

基本信息

CAS(化学文摘登记)号

2223677-61-8

英文名称

Afatinib 杂质 37

英文化学名

(E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

简化分子线性输入规范(SMILES)

O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O)/C=C/CN(C)C

分子式

C20H19ClFN5O2

分子量

415.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 37 is chemically (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Afatinib Impurity 37 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 37 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-37-cas-2223677-61-8/

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Afatinib 杂质 36 CAS号 2044709-79-5

基本信息

CAS(化学文摘登记)号

2044709-79-5

英文名称

Afatinib 杂质 36

英文化学名

(S)-N4-(3,4-dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

简化分子线性输入规范(SMILES)

NC1=CC(C(NC(C=C2)=CC(Cl)=C2Cl)=NC=N3)=C3C=C1O[C@H]4CCOC4

分子式

C18H16Cl2N4O2

分子量

391.3

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 36 is chemically (S)-N4-(3,4-dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Afatinib Impurity 36 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 36 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-36-cas-2044709-79-5/

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Afatinib 杂质 27 CAS号 618061-76-0

基本信息

CAS(化学文摘登记)号

618061-76-0

英文名称

Afatinib 杂质 27

英文化学名

Diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate

简化分子线性输入规范(SMILES)

ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(NC(C[P](OCC)(OCC)=O)=O)C(O[C@H]4CCOC4)=C3)=C1

分子式

C24H27ClFN4O6P

分子量

552.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 27 is chemically Diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate. Afatinib Impurity 27 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 27 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-27-cas-618061-76-0/

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Afatinib Nitroso 杂质 2 CAS号 N/A

基本信息

CAS(化学文摘登记)号

N/A

英文名称

Afatinib Nitroso 杂质 2

英文化学名

(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide

简化分子线性输入规范(SMILES)

ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(NC(/C=C/CN(C)N=O)=O)C(O[C@H]4CCOC4)=C3)=C1

分子式

C23H22ClFN6O4

分子量

500.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Nitroso Impurity 2 is chemically (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide. Afatinib Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-nitroso-impurity-2-cas-N/A/

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Afatinib 杂质 38 CAS号 2223677-65-2

基本信息

CAS(化学文摘登记)号

2223677-65-2

英文名称

Afatinib 杂质 38

英文化学名

N1,N2-bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide

简化分子线性输入规范(SMILES)

O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)C(NC5=CC6=C(NC7=CC=C(F)C(Cl)=C7)N=CN=C6C=C5O[C@@H]8COCC8)=O

分子式

C38H30Cl2F2N8O6

分子量

803.6

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 38 is chemically N1,N2-bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide. Afatinib Impurity 38 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 38 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-38-cas-2223677-65-2/

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Afatinib 杂质 39 CAS号 2223677-66-3

基本信息

CAS(化学文摘登记)号

2223677-66-3

英文名称

Afatinib 杂质 39

英文化学名

(S)-N1-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide

简化分子线性输入规范(SMILES)

O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)C(N(C)C)=O

分子式

C22H21ClFN5O4

分子量

473.9

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 39 is chemically (S)-N1-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide. Afatinib Impurity 39 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 39 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-39-cas-2223677-66-3/

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Afatinib 杂质 33 CAS号 162012-69-3

基本信息

CAS(化学文摘登记)号

162012-69-3

英文名称

Afatinib 杂质 33

英文化学名

7-Fluoro-6-nitroquinazolin-4(3H)-one

简化分子线性输入规范(SMILES)

O=C1NC=NC2=C1C=C([N+]([O-])=O)C(F)=C2

分子式

C8H4FN3O3

分子量

209.1

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 33 is chemically 7-Fluoro-6-nitroquinazolin-4(3H)-one. Afatinib Impurity 33 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 33 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-33-cas-162012-69-3/

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Afatinib 杂质 35 CAS号 2226537-61-5

基本信息

CAS(化学文摘登记)号

2226537-61-5

英文名称

Afatinib 杂质 35

英文化学名

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

简化分子线性输入规范(SMILES)

O=[N+](C1=CC2=C(NC3=CC=C(F)C(F)=C3)N=CN=C2C=C1F)[O-]

分子式

C14H7F3N4O2

分子量

320.2

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 35 is chemically N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine. Afatinib Impurity 35 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 35 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-35-cas-2226537-61-5/

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Afatinib 杂质 32 CAS号 2323570-72-3

基本信息

CAS(化学文摘登记)号

2323570-72-3

英文名称

Afatinib 杂质 32

英文化学名

N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

简化分子线性输入规范(SMILES)

ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(NC(CC(O)CN(C)C)=O)C(O[C@H]4CCOC4)=C3)=C1

分子式

C24H27ClFN5O4

分子量

504.0

物理性质

外观

安全信息

危险品运输编号

非危险品

德国水污染物质分类清单(WGK Germany)

3

详细规格

测试方法

核磁；质谱，液相色谱

保存条件

常温避光保存

产品描述

Afatinib Impurity 32 is chemically N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide. Afatinib Impurity 32 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 32 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

快速询价

邮箱：chemwhat@watson-int.cn

品牌

ChemWhat（凯望）—— 品牌介绍

ChemWhat官网链接地址

https://www.chemwhat.com/afatinib-impurity-32-cas-2323570-72-3/

相关产品

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