Recombinant Human Cyclophilin D (rHuCyP-D)

英文全名

英文别名

PPIF, Cyclophilin F, CyP-M, Rotamase F

蛋白结构

氨基酸序列

CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS

Accession

P30405

Gene ID

10105

产品英文概述

CyP-D is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. CyP-D accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. CyP-D is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

来源

Escherichia coli.

分子量

Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 178 amino acids.

生物活性

No data available

外观

Sterile colorless liquid.

配方

Supplied as a 0.2 um filtered solution in PBS, pH7.4, with 1 mM DTT, 10 % glycerol.

内毒素

Less than 0.1 EU/ug of rHuCyP-D as determined by LAL method.

溶解说明

储存条件

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening.